Homozygote: A person who has two identical forms of a particular gene, one inherited from each parent.
For example, a girl who is a homozygote for cystic fibrosis (CF) received the cystic fibrosis gene from both of her parents and therefore has cystic fibrosis.
The opposite of a homozygote is a heterozygote, a person who has two different forms of a particular gene. For example, the father and mother of a cystic fibrosis child are heterozygotes for cystic fibrosis (CF). Each carries one normal gene and one cystic fibrosis gene but has no signs or symptoms of the disease.