Medical Definition of Phenothiazine

Phenothiazine: One of a group of tranquilizing drugs with antipsychotic actions thought to act by blocking dopaminergic transmission (messages sent using the substance dopamine) within the brain.

Examples of phenothiazines include: chlorpromazine (brand name: Thorazine), fluphenazine (Duraclon), mesoridazine (Serentil), perphenazine (Etrafon and Trilafon), prochlorperazine (Compazine), promazine (Robinul and Anectine), thioridazine (Mellaril), trifluoperazine (Stelazine) and triflupromazine (Robinul).

Quick GuideDementia, Alzheimer's Disease, and Aging Brains

Dementia, Alzheimer's Disease, and Aging Brains

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Last Editorial Review: 5/13/2016

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