Medical Definition of Headache, rebound

Headache, rebound: A headache experienced by someone who has taken pain relievers for migraines or other health conditions and has built up a tolerance for these medications. Often a rebound headache occurs right after the medication wears off. Treatment involves using the medication less frequently or switching to a different pain reliever.

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16 Surprising Headache Triggers and Tips for Pain Relief See Slideshow

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Last Editorial Review: 9/7/2018