FRIDAY, Feb. 19 (HealthDay News) -- Surgery alone offers a reasonable overall level of survival for patients with stage 1 small cell lung cancer, a new study suggests.
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Traditional treatment regimens for limited stage SCLS include chemotherapy and radiotherapy.
In this study, researchers analyzed U.S. National Cancer Institute data on the outcomes of 247 patients with stage 1 SCLC who had surgery to remove a lung (lobectomy).
The three- and five-year survival rates for patients who had surgery alone were 58.1% and 50.3%, respectively. The three- and five-year survival rates for patients who had surgery followed by radiotherapy (RT) were 64.9% and 57.1%, respectively.
"Based on our analysis, surgery without RT may offer a reasonable survival in a selected cohort of patients who undergo lobectomy, but this needs to be validated in a prospective settings," lead investigator Dr. James B. Yu, of Yale University, said in a news release.
"We cannot say conclusively whether patients who endure invasive surgeries can go without additional adjuvant radiation or chemotherapy, but looking forward, the study findings create a platform for advancing the understanding of the role of surgery in therapy."
The study results were published in the February issue of the Journal of Thoracic Oncology.
-- Robert Preidt
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SOURCE: International Association for the Study of Lung Cancer, news release, Feb. 16, 2010
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