Medical Definition of Testosterone replacement therapy

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Testosterone replacement therapy: The practice of giving testosterone to treat conditions in which the testes do not produce enough testosterone. This may be due to absence, injury, or disease.

Testosterone is available in oral, IV/IM, and patch forms. As with estrogen replacement therapy for women, dosing must be carefully calibrated to gain the greatest benefits without unwanted side-effects.

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Last Editorial Review: 1/26/2017

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