Medical Definition of Testosterone replacement therapy

Testosterone replacement therapy: The practice of giving testosterone to treat conditions in which the testes do not produce enough testosterone. This may be due to absence, injury, or disease.

Testosterone is available in oral, IV/IM, and patch forms. As with estrogen replacement therapy for women, dosing must be carefully calibrated to gain the greatest benefits without unwanted side-effects.

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Last Editorial Review: 1/26/2017