Medical Definition of Blister

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Blister: A collection of fluid underneath the top layer of skin (epidermis). There are many causes of blisters, including burns, friction forces, and diseases of the skin. Also known as bleb and bulla.

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Reviewed on 12/27/2018

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