Medical Definition of Cholesterol ester transfer protein

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Cholesterol ester transfer protein: A protein that helps regulate the size of cholesterol particles and influence the process of atherogenesis (the formation of plaques in arteries). Abbreviated CETP. The CETP gene is in chromosome band 16q21. A number of mutations are known in the CETP gene. Some result in CEPT deficiency, increased levels of HDL ("good") cholesterol and unusually large cholesterol particles. CETP deficiency appears to be a good mutation which is antiatherogenic and may confer unusual longevity to the person. Also called cholesteryl ester transfer protein.

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Reviewed on 12/21/2018

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