Reviewed on 6/11/2021
Other Name(s):

Crest Marine, Criste-Marine, Criste Marine, Crithme, Crithmum maritimum, Fenouil Marin, Perce-Pierre, Peter's Cress, Pierce-Stone, Salicornia, Sampier, Sea Fennel.


Samphire is a plant. The parts that grow above the ground are used as medicine.

People take samphire to treat and prevent scurvy, a disease caused by a lack of vitamin C.

How does it work?

Samphire contains vitamin C, which is used to treat and prevent scurvy.


Vitamin D Deficiency: How Much Vitamin D Is Enough? See Slideshow

Uses & Effectiveness

Insufficient Evidence to Rate Effectiveness for...

  • Scurvy, a vitamin-C deficiency disease.
  • Other conditions.
More evidence is needed to rate the effectiveness of samphire for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Side Effects

Samphire might be safe for most people, but the possible side effects are unknown.


Next to red peppers, you can get the most vitamin C from ________________. See Answer

Special Precautions & Warnings

Pregnancy and breast-feeding: Not enough is known about the use of samphire during pregnancy and breast-feeding. Stay on the safe side and avoid use.


LithiumInteraction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Samphire might have an effect like a water pill or "diuretic." Taking samphire might decrease how well the body gets rid of lithium. This could increase how much lithium is in the body and result in serious side effects. Talk with your healthcare provider before using this product if you are taking lithium. Your lithium dose might need to be changed.


The appropriate dose of samphire depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for samphire. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.

Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.