Reviewed on 6/11/2021
Other Name(s):

Molécules de Triglycérides Acylés à Chaînes Courtes et Longues, Short- and Long-Chain Acyl Triglyceride Molecules.


Salatrim is a man-made chemical. It is used as a fat replacement.

People take salatrim for weight loss.

In foods, salatrim is added to reduce fat without reducing how full a person feels after eating the food.

How does it work?

Salatrim might help people feel full. This might help with weight loss.


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Uses & Effectiveness

Insufficient Evidence to Rate Effectiveness for...

More evidence is needed to rate the effectiveness of salatrim for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Side Effects

Salatrim is LIKELY SAFE when taken by mouth in food amounts. Salatrim is POSSIBLY SAFE when taken by mouth in doses of 30 grams daily. Mild stomach discomfort has been reported for some people who used salatrim.


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Special Precautions & Warnings

Pregnancy and breast-feeding: Not enough is known about the use of salatrim during pregnancy and breast-feeding. Stay on the safe side and avoid use.


The appropriate dose of salatrim depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for salatrim. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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Byrne, David. COMMISSION DECISION of 1 December 2003 authorising the placing on the market of salatrims as novel food ingredients under Regulation (EC) No 258/97 of the European Parliament and of the Council. Official Journal of the European Commission. Updated December 13, 2003. Retrieved January 27, 2015.

Finley JW, Leveille GA, Dixon RM, et al. Clinical Assessment of SALATRIM, a reduced-calorie triacylglycerol. J Agric Food Chem 1994;42(2):581-596.

Livesey G. The absorption of stearic acid from triacylglycerols: an inquiry and analysis. Nutr Res Rev 2000;13(2):185-214. View abstract.

Senanayake SPJN, Shahidi F. "Dietary fat substitutes." Bailey's Industrial Oil and Fat Products, Sixth Edition, 6 Volume Set. Volume 3: Edible oil and fat products: Specialty oils and oil products. Ed. Shahidi F. Hoboken, NJ: John Wiley & Sons, 2005.

Smith RE, Finley JW, Leveille GA. Overview of SALATRIM, a family of low-calorie fats. J Agric Food Chem 1994;42:432-434.

Sorensen LB, Cueto HT, Andersen MT, et al. The effect of salatrim, a low-calorie modified triacylglycerol, on appetite and energy intake. Am J Clin Nutr 2008;87(5):1163-1169. View abstract.

Tuomasjukka S, Viitanen M, Kallio H. Stearic acid is well absorbed from short- and long-acyl-chain triacylglycerol in an acute test meal. Eur J Clin Nutr 2007;61(12):1352-1358. View abstract.