Sage: Common, Garden, and Black Sage

What is sage leaf? How does it work (mechanism of action)?

Sage leaf is a spice that is used as herbal supplement for several conditions. The mechanism of action of Sage leaf is not known. It is believed to provide therapeutic effect through beta-thujone, which is a major component of Sage leaf oil extract.

You do not need a prescription to obtain sage.

What is sage used for?

Sage is a herbal supplement which can be used as:

  • A natural remedy as treatment for Alzheimer's disease.

To treat:

What are the side effects of sage?

Side effects of Sage leaf are;

What is the dosage for sage?

  • Tincture: Take 1/8 to 1/2 teaspoon of dried sage leaves in a sip of water up to two times a day.
  • Herbal Tea: Drink several cups of sage tea every day for several weeks.
  • Gargle or take small sips of sage tea: Gargle or drink throughout the day as needed.
  • Alzheimer's disease: Take up to 1 gram of sage by mouth per day.
  • Genital herpes: Apply 23 mg per day of sage extract and rhubarb extract cream to affected areas every 2 to 4 hours for 10 to 14 days.

Which drugs or supplements interact with sage?

Sage leaf should be used with caution with medications that cause sedation, due to increased sedative effects.


According to the USDA, there is no difference between a “portion” and a “serving.” See Answer

Is sage safe to take if you are pregnant or breastfeeding?

  • There are no adequate studies done on Sage leaf to determine safe and effective use in pregnant women.
  • It is not known whether Sage leaf enters breast milk; therefore, it is best to be cautious before using in nursing mothers.

What else should you know about sage?

What preparations of sage leaf-oral are available?

Sage leaf is available in tablets, tincture, cream and tea forms.

How should I keep sage leaf-oral stored?

Due to multiple manufacturers making Sage leaf, storage requirements may vary based on manufacturer practices.


Salvia officinalis (Sage Leaf, Common Sage, Garden Sage, Black Sage) is a spice in which the leaves are used as an herbal supplement for several conditions. Side effects, drug interactions, dosage, and pregnancy safety information should be reviewed prior to taking this herbal supplement.

Treatment & Diagnosis

Prevention & Wellness

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

FDA Prescribing Information.
Medically reviewed by John C. Cunha, DO.