- What is ropinirole-oral, and how does it work (mechanism of action)?
- What brand names are available for ropinirole-oral?
- Is ropinirole-oral available as a generic drug?
- Do I need a prescription for ropinirole-oral?
- What is the dosage for ropinirole-oral?
- Which drugs or supplements interact with ropinirole-oral?
- Is ropinirole-oral safe to take if I'm pregnant or breastfeeding?
- What else should I know about ropinirole-oral?
What is ropinirole-oral, and how does it work (mechanism of action)?
Ropinorole is an anti-Parkinson's medication. Ropinorole works by binding to dopamine receptors in the brain. Ropinorole stimulates the dopamine receptors and improves symptoms of Parkinson's disease. The FDA approved ropinirole in September 1997. It is also a treatment for Restless legs syndrome (RLS ).
What is the dosage for ropinirole-oral?
Immediate-release tablets: Take 0.25 mg by mouth 3 times a day for week 1, then increase weekly by 0.25 mg 3 times a day if needed. After week 4 doses may be increased by 1.5 mg/day on weekly basis up to a dose of 9 mg/day. If still needed, may increase doses by 3 mg/day on a weekly basis to a total dose of 24 mg/day.
Extended-release tablets: Take 2 mg by mouth once daily for 1 to 2 weeks. Doses can be increased by 2 mg/day at intervals longer than week. Not to exceed 24 mg/day.
Restless Leg Syndrome (RLS)
Immediate release tablets: Take 0.25 mg by mouth 1 to 3 hours before bedtime on day 1 and 2. Starting day 3 to 7, may increase to 0.5 mg by mouth once daily at bedtime. Starting week 2, may increase to 1 mg per day, then increase weekly by 0.5 mg/day to up to 4 mg/day.
Which drugs or supplements interact with ropinirole-oral?
Ropinorole should not be used with phenothiazine, atypical antipsychotics. and metoclopramide (Reglan) because these drugs block dopamine receptors and lead to decreased effectiveness of ropinorole. Examples of phenothiazines include prochlorperazine (Compazine), fluphenazine (Permitil), and trifluoperazine (Stelazine). Examples of atypical antipsychotics include aripiprazole (Abilify), olanzapine (Zyprexa), quetiapine (Seroquel), and rispepridone (Risperdal).
Is ropinirole-oral safe to take if I'm pregnant or breastfeeding?
There are no adequate studies of ropinorole to determine safe and effective use in pregnant women.
SIDE EFFECTS: Patients treated with ropinirole have reported falling asleep during activities of daily living, including driving. Other side effects of ropinorole are nausea, flatulence, dizziness, sleepiness, fatigue, flushing, hallucinations, confusion, irregular heart rate and rhythm, and confusion.
What else should I know about ropinirole-oral?
What preparations of ropinirole-oral are available?
Tablets (immediate release): 0.25, 0.5, 1, 2, 3, 4, 5 mg. Tablets (extended-release): 2, 4, 6, 8, 12 mg
How should I keep ropinirole-oral stored?
STORAGE Store ropinorole immediate-release and extended-release tablets between temperatures 15 C and 30 C (59 F and 86 F).
Ropinorole hydrochloride (Requip, Requip XL) is a medication prescribed to treat the signs and symptoms of Parkinson's disease and moderate-to-severe restless leg syndrome (RLS). Side effects, drug interactions, dosage, storage, and pregnancy safety information should be reviewed prior to using this medicaiton.
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