What is Lactated Ringer's solution, and how does it work (mechanism of action)?

Lactated Ringer's is a sterile solution for fluid and electrolyte replenishment. It restores fluid and electrolyte balances, produces diuresis, and acts as alkalizing agent (reduces acidity). The FDA approved Ringer's solution in plastic containers in 1971.

What brand names are available for Lactated Ringer's solution?

Lactated Ringer's solution

Is Lactated Ringer's solution available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for Lactated Ringer's solution?

Yes

What are the uses for Lactated Ringer's solution?

Lactated Ringer's is used for balancing fluid and electrolytes and as an alkalizing agent.

What are the side effects of Lactated Ringer's solution?

Side effects of Lactated Ringer's solution are

What is the dosage for Lactated Ringer's solution?

Adult dosing of Lactated Ringer's solution is as directed by the physician. Dosing is individualized based on the patient's age, weight, ongoing treatment, and clinical condition.

Safe and effective use of Lactated Ringer's solution in children is based on clinical practice.

Which drugs or supplements interact with Lactated Ringer's solution?

Lactated Ringer's solution should not be mixed with ceftriaxone (Rocephin) due to the significant risk of ceftriaxone and calcium precipitation.

QUESTION

According to the USDA, there is no difference between a “portion” and a “serving.” See Answer

Is Lactated Ringer's solution safe to take if I'm pregnant or breastfeeding?

There are no adequate studies done on Lactated Ringer's solution to determine safe and effective use in pregnant women.

Use by women who are breastfeeding mothers has not been adequately evaluated.

What else should I know about Lactated Ringer's solution?

What preparations of Lactated Ringer's solution are available?

Lactated Ringer's solution is available in 250 ml, 500 ml, and 1000 ml in specific plastic containers.

  • Lactated Ringer's is composed of sodium chloride 6 g/L, sodium lactate 3.1 g/L, potassium chloride 0.3 g/L, and calcium chloride 0.2 g/L.
  • Lactated Ringer's contains ions of sodium 130 mEq/L, potassium 4 mEq/L, calcium 2.7 mEq/L, chloride 109 mEq/L, and lactate 28 mEq/L.
  • Lactated Ringer's has an osmolarity of 273 mOsmol/L, pH of 6.5, and caloric content of 9 kcal/L.

How should I keep Lactated Ringer's solution stored?

Store Lactated Ringer's solution at room temperature of 25 C, avoiding excessive heat. Brief exposure to up to 40 C does not affect the product.

Summary

Sodium chloride, potassium chloride, sodium lactate and calcium (Lactated Ringer's solution) is a sterile solution used to replace fluids and electrolytes in patients with unbalanced blood fluid, and it also is used for an alkalizing agent. Review side effects, drug interactions, dosage, storage, and pregnancy safety information prior to using this medication.

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Medically Reviewed on 7/1/2019
References
FDA Prescribing Information.
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