- Heartburn Slideshow: Foods to Eat, Foods to Avoid
- 10 Facts About the Amazing Brain
- Weight Gain Shockers Slideshow Pictures
- What is rimantadine, and how does it work (mechanism of action)?
- What brand names are available for rimantadine?
- Is rimantadine available as a generic drug?
- Do I need a prescription for rimantadine?
- What are the side effects of rimantadine?
- What is the dosage for rimantadine?
- Which drugs or supplements interact with rimantadine?
- Is rimantadine safe to take if I'm pregnant or breastfeeding?
- What else should I know about rimantadine?
What is rimantadine, and how does it work (mechanism of action)?
Rimantadine is a synthetic (man-made) anti-viral drug that can prevent viruses in cells from multiplying. Rimantadine is chemically related to amantadine (Symmetrel), but rimantadine has fewer side effects on the nervous system than amantadine. It is useful in treating and preventing influenza A virus in adults and in preventing influenza A virus in children. However, the Center for Disease Control and Prevention recommends that rimantadine should not to be used to replace the annual influenza vaccination. Prolonged and frequent use of rimantadine can cause it to be less effective in its activity against the influenza A virus. Rimantadine is most effective when given within 48 hours of the start of symptoms associated with the influenza A. The FDA approved rimantadine in September 1993.
What is the dosage for rimantadine?
The dose of rimantadine in adults for both prevention and treatment of the influenza virus infection is one, 100 mg tablet taken twice daily with or without food. If it causes an upset stomach, it can be taken with food. The usual dose of rimantadine for prevention of the influenza virus in children is 5 mg/kg daily given in two divided doses. If used for treatment of an established infection, rimantadine should be started as soon as possible, preferably within 48 hours after the onset of symptoms. It should be continued for 5 to 7 days from when symptoms began and stopped soon after symptoms disappear.
Which drugs or supplements interact with rimantadine?
Rimantadine may reduce the effectiveness of influenza virus vaccine. It is recommended that rimantadine not be given 48 hours prior to and 14 days after administering the influenza virus vaccine. Rimantadine may interact with monoamine oxidase inhibitors (MAOIs), for example, isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and procarbazine (Matulane), and cause the blood pressure to drop suddenly.
Is rimantadine safe to take if I'm pregnant or breastfeeding?
There are no well-controlled studies of rimantadine in pregnant women and, therefore, rimantadine is not recommended during pregnancy. Other drugs including oseltamivir (Tamiflu) and zanamivir (Relenza) are recommended for the prevention and treatment of influenza A virus illness in pregnant women.
It is not recommended that mothers who are breastfeeding use rimantadine due to possible risks of adverse effects in infants.
rimantadine (Flumadine) is a medication prescribed for the treatment and prevention of influenza A in adults, and for the prevention of the influenza A virus in children older than one year of age. Side effects, drug interactions, and pregnancy safety information should be reviewed prior to taking this medication.
Multimedia: Slideshows, Images & Quizzes
Cold & Flu Quiz: Influenza vs. Common Cold
Aches? Pain? Fever? This Cold & Flu Quiz tests your knowledge on the difference between coming down with the common cold and...
Picture of Influenza Virus
The flu is caused by viruses that infect the respiratory tract which are divided into three types, designated A, B, and C. See a...
Natural Remedies for Cold and Flu
What natural remedies work for the flu and common cold? Many claim cold symptoms and flu symptoms can be relieved with Echinacea,...
10 Foods to Eat When You Have the Flu in Pictures
If you're sick with the flu, you'll want to know the best foods to make you feel better. Learn some of the soothing, nutritious...
Cold, Fever and Flu Treatment in Children: Medications and Home Remedies
Colds and fevers are some of the most common ailments in children. Learn common cold symptoms, treatment options, over the...
Related Disease Conditions
Novel H1N1 influenza A virus infection (swine flu) is an infection that generally is transferred from an infected pig to a human,...
Influenza (flu) is a respiratory illness caused by a virus. Flu symptoms include fever, cough, sore throat, runny nose, headache,...
Bird Flu (Avian Influenza, Avian Flu)
Bird flu (avian flu, avian influenza) infection in humans may result from contact with infected poultry. There is a vaccine to...
Cold, Flu, Allergy Treatments
Before treating a cold, the flu, or allergies with over-the-counter (OTC) medications, it's important to know what's causing the...
Pregnancy: Swine Flu and the H1N1 Vaccine
Pregnant and women who are breastfeeding are encouraged to receive the seasonal flu shot as well as the 2009 H1N1 influenza...
Treatment & Diagnosis
- Cold & Flu FAQs
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Drugs: Buying Prescription Drugs Online Safely
- Drugs: The Most Common Medication Errors
- Medication Disposal
- Dangers of Mixing Medications
- Flu: What to Do if You Get the Flu
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
Prevention & Wellness
Drugs and Treatment Resources
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Reference: FDA Prescribing Information