Reye's Syndrome: Symptoms & Signs

Medically Reviewed on 8/11/2020

Reye's syndrome is a rare but often severe illness that primarily occurs in children and adolescents.

The first signs and symptoms of Reye's syndrome are

Other associated signs and symptoms can include

In some cases, the illness can lead to coma and death.

Cause of Reye's syndrome

Although the cause of Reye's syndrome is unclear, studies have identified that it appears to follow some viral infections and the use of aspirin medications in children and teens. Most children who develop the condition have a history of a recent viral infection, and in many cases, a caregiver gave the child aspirin as the treatment for the infection.

Other reye's syndrome symptoms and signs

  • Confusion
  • Decreased Level of Consciousness
  • Disorientation or Hallucinations
  • Excessive Lethargy
  • Irritable, Aggressive, or Irrational Behavior
  • Mental Status Changes
  • Seizures
  • Vomiting
  • Weakness or Paralysis in the Arms and Legs


The abbreviated term ADHD denotes the condition commonly known as: See Answer

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Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.