- What is ranitidine, and how does it work (mechanism of action)?
- What are the uses for ranitidine?
- What are the side effects of ranitidine?
- What is the dosage for ranitidine?
- Which drugs or supplements interact with ranitidine?
- Is ranitidine safe to take if I'm pregnant or breastfeeding?
- What else should I know about ranitidine?
What is ranitidine, and how does it work (mechanism of action)?
Ranitidine is an oral drug that blocks the production of acid by acid-producing cells in the stomach. It belongs to a class of drugs called H2 (histamine-2) blockers that also includes cimetidine (Tagamet), nizatidine (Axid), and famotidine (Pepcid). Histamine is a naturally occurring chemical that stimulates cells in the stomach (parietal cells) to produce acid. H2-blockers inhibit the action of histamine on the cells, thus reducing the production of acid by the stomach. Since excessive stomach acid can damage the esophagus, stomach, and duodenum and lead to inflammation and ulceration, reducing stomach acid prevents and heals acid-induced inflammation and ulcers. The FDA approved ranitidine in October 1984.
What brand names are available for ranitidine?
Zantac, Zantac 75, Zantac 150 Maximum Strength, Deprizine FusePaq
Is ranitidine available as a generic drug?
GENERIC AVAILABLE: yes
Do I need a prescription for ranitidine?
yes; OTC (Zantac 75 and 150 mg)
What are the side effects of ranitidine?
Minor side effects occur and these are:
Other important, but rare, side effects include:
What is the dosage for ranitidine?
Ranitidine may be taken with or without food.
- Usual oral doses for treating ulcers and GERD are 150 mg twice daily or 300 mg at bedtime. The maintenance dose is 150 mg daily.
- Erosive esophagitis is treated with 150 mg 4 times daily.
- Zollinger-Ellison syndrome may be treated with as much as 6 g daily.
- Heartburn is treated with 75 mg or 150 mg once or twice daily 30-60 minutes before consuming meals or beverages that cause heartburn.
Self-medication should not last longer than 2 weeks unless advised by a physician.
Which drugs or supplements interact with ranitidine?
Ranitidine, like other drugs that reduce stomach acid, may interfere with the absorption of drugs that require acid for adequate absorption. Examples include iron salts (for example iron sulphate), itraconazole (Sporanox), and ketoconazole (Nizoral, Extina, Xolegel, Kuric).
Is ranitidine safe to take if I'm pregnant or breastfeeding?
Ranitidine is secreted into human breast milk and may pose a potential risk to the infant.
What else should I know about ranitidine?
What preparations of ranitidine are available?
Tablets or Capsules: 25, 75, 150 and 300 mg; Syrup: 15 mg/ml; Injection: 1 mg/ml or 25 mg/ml.
How should I keep ranitidine stored?
Tablets should be stored at room temperature between 15 C – 30 C (59 F - 86 F) in a tightly closed container. Syrup and injection should be stored between 4 C and 25 C (39 F and 77 F).
Ranitidine (Zantac) is a drug used for the treatment and prevention of stomach and duodenum ulcers. It is also used to treat heartburn, inflammation of the esophagus, and Zollinger-Ellison syndrome. Review side effects, drug interactions, dosage, and pregnancy safety information prior to taking any medication.
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GERD (Acid Reflux, Heartburn)
GERD (gastroesophageal reflux disease) is a condition in which the acidified liquid contents of the stomach backs up into the esophagus. The symptoms of uncomplicated GERD are: heartburn, regurgitation, and nausea. Effective treatment is available for most patients with GERD.
Peptic Ulcer (Stomach Ulcer)
Peptic or stomach ulcers are ulcers are an ulcer in the lining of the stomach, duodenum, or esophagus. Ulcer formation is related to H. pylori bacteria in the stomach, use of anti-inflammatory medications, and cigarette smoking. Symptoms of peptic or stomach ulcers include abdominal burning or hunger pain, indigestion, and abdominal discomfort after meals. Treatment for stomach ulcers depends upon the cause.
Reflux Laryngitis (Diet, Home Remedies, Medicine)
Reflux laryngitis is caused by acid refluxing back up through the esophagus and voice box. Reflux laryngitis causes irritation and inflammation of the lining of the esophagus, larynx, and throat; and can lead to symptoms, signs, and other problems like esophagitis, sinusitis, strictures, throat clearing, swallowing problems, asthma, chronic cough, and growths on the vocal cords. Typical symptoms of reflux laryngitis include heartburn, hoarseness, or a sensation of a foreign body in the throat. Reflux laryngitis can be treated with diet chanes, OTC medication, prescription medication, and lifestyle changes.
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Cough (Chronic, Persistent Cough in Adults and Children)
Chronic cough is a cough that does not go away and is generally a symptom of another disorder such as asthma, allergic rhinitis, sinus infection, cigarette smoking, GERD, postnasal drip, bronchitis, pneumonia, medications, and less frequently tumors or other lung disease. Chronic cough treatment is based on the cause, but may be soothed natural and home remedies.
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Esophagitis (Pain, Symptoms, Causes, Grades, and Cure)
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Heartburn is a burning sensation experienced from acid reflux (GERD). Symptoms of heartburn include chest pain, burning in the throat, difficulty swallowing, the feeling of food sticking in the throat, and a burning feeling in the chest. Causes of heartburn include dietary habits, lifestyle habits, and medical causes. Treatments for heartburn include lifestyle changes, OTC medication,prescription medication, and surgery.
Cyclic Vomiting Syndrome (CVS)
Cyclic vomiting syndrome is a condition in which affected individuals have severe nausea and vomiting that come in cycles. Researchers believe that cyclic vomiting syndrome and migraine headaches are related. Triggers of cyclic vomiting syndrome are emotional stress and infections. People with cyclic vomiting syndrome are at an increased risk of dehydration. Cyclic vomiting syndrome is difficult to diagnose. Treatment varies from person to person, but is generally directed toward relief of the symptoms of the condition.
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