About 10%-15% of people with psoriasis -- a chronic inflammatory skin condition that causes changes in the skin, including raised, reddened patches of skin with silvery white scales -- also develop arthritis. The inflammation of the skin can precede the joint inflammation by years in some cases. Symptoms of psoriatic arthritis arise from inflammation and resemble those of other kinds of arthritis. The joints of the knees, ankles, and feet are commonly involved. Psoriatic arthritis can also cause inflammation in the spine and the eyes, skin, heart, kidneys, mouth, and various organs and is one of the forms of arthritis known as "spondyloarthropathies."
Psoriatic arthritis symptoms and signs include
- joint aches and stiffness,
- joint swelling,
- joint warmth and redness,
- joint pain and tenderness,
- loss of range of motion of the affected joints.
If the spine is affected, there can be pain and stiffness in the low back, buttocks, neck, and upper back. Tendons can also become inflamed, and if Achilles tendinitis is present, other symptoms can include limping, pain with walking, and pain with climbing stairs. Inflammation of the chest wall, lungs, and aorta can cause chest pain and shortness of breath. Enthesitis, or the inflammation of the areas at which ligaments and tendons meet the bone, is often a feature of psoriatic arthritis. If untreated, psoriatic arthritis can ultimately lead to joint damage and physical deformity of the joints.
REFERENCE:
Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.
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Psoriatic Arthritis Symptoms and Signs
- Acne
- Back Pain
- Back Stiffness
- Buttock Pain
- Chest Pain
- Decreased Appetite
- Eye Pain
- Fatigue
- Finger Swelling
- Joint Pain
- Joint Redness
- Joint Stiffness
- Joint Tenderness
- Limping
- Muscle Aches
- Muscle Stiffness
- Nail Changes
- Nail Pitting
- Neck Pain
- Neck Stiffness
- Pain With Walking
- Shortness of Breath
- Swollen Joints
- Toe Swelling
- Warmth of Joints
- Acne
- Back Pain
- Back Stiffness
- Buttock Pain
- Chest Pain
- Decreased Appetite
- Eye Pain
- Fatigue
- Finger Swelling
- Joint Pain
- Joint Redness
- Joint Stiffness
- Joint Tenderness
- Limping
- Muscle Aches
- Muscle Stiffness
- Nail Changes
- Nail Pitting
- Neck Pain
- Neck Stiffness
- Pain With Walking
- Shortness of Breath
- Swollen Joints
- Toe Swelling
- Warmth of Joints
Examples of Medications for Psoriatic Arthritis Symptoms and Signs
- adalimumab, Humira
- apremilast (Otezla)
- aspirin (acetylsalicylic acid, Bayer, Ecotrin, and others)
- celecoxib (Celebrex)
- certolizumab, Cimzia
- diclofenac, Voltaren, Cataflam, Voltaren-XR, Cambia
- etanercept, Enbrel
- golimumab (Simponi, Simponi Aria)
- hydroxychloroquine (Plaquenil)
- ibuprofen (Advil, Children's Advil/Motrin, Medipren, Motrin, Nuprin, PediaCare Fever, and others)
- indomethacin, Indocin, Indocin-SR (Discontinued Brand in U.S.)
- infliximab, Remicade
- leflunomide, Arava
- methotrexate, Rheumatrex, Trexall
- naproxen (Aleve, Anaprox, Naprelan, Naprosyn)
- Remicade vs. Humira
- sulfasalazine, Azulfidine
- sulindac, Clinoril
- tolmetin, Tolectin (Discontinued Brand)
- ustekinumab, Stelara
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