GENERIC NAME: PROPANTHELINE - ORAL (proe-PAN-the-leen)
USES: Propantheline is used with other medications to treat peptic ulcers. It works by decreasing the release of acid in the stomach.OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This drug may also be used with other medications to treat extra stomach acid (e.g., Zollinger-Ellison syndrome) or certain bowel disorders (e.g., irritable bowel syndrome). For bowel disorders, the medication works by decreasing the movement of the stomach/intestines.
HOW TO USE: Take this medication by mouth, usually 30 minutes before each meal and at bedtime or as directed by your doctor.Dosage is based on your medical condition and response to therapy.Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.Inform your doctor if your condition persists or worsens.
SIDE EFFECTS: Dry mouth, decreased sweating, dizziness, drowsiness, blurred vision, widened pupils, nausea/vomiting, or constipation may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes, eye pain/pressure, fast/pounding heartbeat, difficulty urinating.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
PRECAUTIONS: Before taking propantheline, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: glaucoma, myasthenia gravis, movement/blockage disorders of the stomach/bowels (e.g., paralytic ileus, pyloroduodenal stenosis, achalasia, intestinal atony), difficulty urinating (e.g., prostatic hypertrophy), severe ulcerative colitis.Before using this medication, tell your doctor or pharmacist your medical history, especially of: overactive thyroid (hyperthyroidism), liver disease, kidney disease, high blood pressure, heart/blood vessel disease (e.g., congestive heart failure, coronary artery disease, tachycardia), esophagus problems (e.g., GERD), nerve disorders (e.g., autonomic neuropathy), diarrhea, breathing problems (e.g., asthma), mild/moderate ulcerative colitis.Before having surgery, tell your doctor or dentist that you are using this medication.This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.This medication can decrease sweating. To prevent heatstroke, avoid becoming overheated in hot weather, in saunas, and during exercise/other strenuous activities.Caution is advised when using this drug in the elderly because they may be more sensitive to the side effects.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medication because a very serious interaction may occur: pramlintide.If you are currently using the medication listed above, tell your doctor or pharmacist before starting propantheline.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: antihistamines (e.g., diphenhydramine, meclizine), antispasmodics (e.g., dicyclomine), belladonna alkaloids (e.g., scopolamine, atropine), certain antiarrhythmic drugs (e.g., quinidine, procainamide), certain drugs for Parkinson's disease (e.g., amantadine, levodopa, benztropine, trihexyphenidyl), corticosteroids (e.g., prednisone), digoxin (slow-dissolving type), drugs that affect stomach movement (e.g., metoclopramide), drugs which depend on stomach acidity (e.g., ketoconazole), MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine), phenothiazines (e.g., promethazine, chlorpromazine), potassium tablets/capsules, tricyclic antidepressants (e.g., amitriptyline).Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., meperidine, codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, trazodone).Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about using those products safely.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: mental/mood changes, fainting, muscle weakness, fast/irregular heartbeat, hot/dry skin, trouble breathing.
MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Information last revised March 2013. Copyright(c) 2013 First Databank, Inc.
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Peptic Ulcer (Stomach Ulcer)
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Nerve Disease and Bladder Control
A nerve problem might affect your bladder control if the nerves that are supposed to carry messages between the brain and the bladder do not work properly. Such problems include urine retention, poor control of sphincter muscles, and overactive bladder. Treatment depends upon the cause of the nerve damage and resulting type of bladder control problem.
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