- What is pramoxine, and how does it work (mechanism of action)?
- Is it available as a generic drug?
- Do I need a prescription for pramoxine?
- What are the uses for pramoxine?
- What are the side effects and adverse effects of pramoxine?
- What is the dosage for pramoxine?
- Which drugs or supplements interact with this medication?
- What brand names are available for pramoxine?
- Is this drug safe to use during pregnancy or while breastfeeding?
- What else should I know about pramoxine?
What is pramoxine, and how does it work (mechanism of action)?
Pramoxine is a topical (used on the skin) anesthetic (numbing agent). Topical anesthetics are chemicals that interfere with the function of the nerves that sense pain. Pramoxine may be used in persons who are allergic to other local anesthetics such as lidocaine, procaine, or benzocaine.
Do I need a prescription for pramoxine?
Yes, you need a prescription from your doctor or other health care professional to obtain this medication.
What are the uses for pramoxine?
What are the side effects and adverse effects of pramoxine?
In some patients, pramoxine may act as a "sensitizer," and:
- Worsen skin conditions
- Cause burning
- Cause stinging
What is the dosage for pramoxine?
- Apply one dose topically to the affected areas 3 to 4 times per day.
- This drug is intended only for external use and should not be applied to open cuts or wounds or damaged skin.
- If the condition does not improve after 7 days of use, a doctor, pharmacist, or other health care professional should be consulted.
Latest Skin News
Which drugs or supplements interact with this medication?
There are no drug interactions listed for this medication.
What brand names are available for pramoxine?
There are numerous brand names for pramoxine, far too many to list here. Examples include:
- Sarna Sensitive
The brand Anti-Itch has been discontinued in the US.
Is this drug safe to use during pregnancy or while breastfeeding?
What else should I know about pramoxine?
This medication is available in formulations of:
- Topical Cream: 1%
- Topical Gel: 1%
- Topical Lotion: 1%
- Topical Spray: 1%
Keep this medication stored at room temperature, 15 C-30 C (59 F-86 F).
Subscribe to MedicineNet's General Health Newsletter
- Insect bites
- Poison ivy
- Poison sumac
- Vaginal itching
In some patients pramoxine may act as a "sensitizer" and cause side effects of:
- Worsening of the skin condition
- Burning or stinging of the skin
Multimedia: Slideshows, Images & Quizzes
Atopic Eczema (Atopic Dermatitis) Quiz: Test Your Skin Disorders IQ
Does dry, itchy, flaky, scaly, red, inflamed skin sound familiar to you? Take the Atopic Eczema (Atopic Dermatitis) Quiz to learn...
Summer Skin Risks: Sunburn, Bug Bites & Poison Ivy
When it comes to summer, there plenty of hazards under the sun! Take the Summer Skin Hazards Quiz and clue in on the dangers to...
Bed Bugs Quiz: How to Get Rid of Bed Bugs
That unexplained itching could be caused by bedbugs. Take the Bedbugs Quiz to learn the causes and symptoms of a bedbug...
Hemorrhoids Quiz: Test Your Medical IQ of Piles
Does everyone have hemorrhoids? Test your knowledge of this and many other facts about Hemorrhoids.
Picture of Sunburn
Sunburn is an inflammation of the skin that develops in response to exposure to ultraviolet (UV) radiation from the sun or from...
Picture of Eczema
A particular type of inflammatory reaction of the skin in which there are typically vesicles (tiny blister-like raised areas) in...
Picture of Acute Sunburn
Sunburn is an acute, delayed, and transient inflammatory response of normal skin after exposure to UVR from sunlight or...
Picture of Cold Sores Treatment
You can't cure HSV or a cold sore, but you can alleviate the pain it causes by avoiding spicy or acidic foods, applying ice, and...
Picture of Hemorrhoid
A dilated (enlarged) vein in the walls of the anus and sometimes around the rectum, usually caused by untreated constipation but...
Picture of Bedbugs
Adult bed bugs are wingless insects about one-quarter of an inch long and oval in shape. See a picture of Bedbug and learn more...
Picture of Urticaria
This is a close-up view of wheals with white-to-light-pink color centrally and peripheral erythema. See a picture of Urticaria...
Picture of Cold Sores (Fever Blisters)
Cold sores, sometimes called fever blisters, are groups of small blisters on the lip and around the mouth. See a picture of Cold...
Picture of Atopic Dermatitis or Eczema
Eczema is a skin condition caused by inflammation. See a picture of Atopic Dermatitis or Eczema and learn more about the health...
Picture of Bedbug Bites
The first sign of bedbugs may be red, itchy bites on the skin, usually on the arms or shoulders. See a picture of Bedbug Bites...
Picture of Fire Ant Bites
The fire ant sting typically causes red hive-like lesions that burn and itch. See a picture of Fire Ant Bites and learn more...
Picture of Flea Bites
Some people are very sensitive to flea bites -- but scratching can cause a wound or infection. See a picture of Flea Bites and...
Picture of Rash from Poisonous Plants
Poison ivy, poison oak and poison sumac are plants that contain an irritating, oily sap called urushiol. See a picture of Rash...
Picture of Sunburn (First-Degree Burns)
A sunburn is skin damage from the sun's ultraviolet (UV) rays. See a picture of Sunburn (First-Degree Burns) and learn more about...
Picture of Sunburn (Second-Degree)
Your skin type affects how easily you become sunburned. See a picture of Sunburn (Second-Degree) and learn more about the health...
Picture of Poison Ivy
Poison ivy has characteristic shiny, red, three-leaf configuration. See a picture of Poison Ivy and learn more about the health...
Bad Bugs: Identify Insects and Bug Bites
What do bed bug bites look like? How do you treat bug bites? Why do bug bites burn? See spider bite pictures and learn how to...
Sun-Damaged Skin: Pictures of Sun Spots, Wrinkles, Sunburns
See how sun damaged skin can cause wrinkles, moles, melanoma (skin cancer) and more. Explore sunburn relief and how actinic...
Bed Bug Bites: Fighting Back Against Bedbugs
What does a bedbug look like? Learn to ID bedbugs and bedbug bites. Get tips on how to prevent, treat, and get rid of bedbugs.
Summer Skin-Hazard Pictures: Stings, Bites, Burns, and More
Don't let spider bites, sunburn, poison ivy, chigger bites, and jellyfish stings sabotage your healthy skin. Learn how you can...
Cold Sores Causes, Remedies, & Diagnosis
How to get rid of cold sores? First learn about the herpes virus and how it causes cold sores. When are cold sores contagious?...
Eczema (Atopic Dermatitis) Causes, Symptoms, Treatment
Eczema (Atopic Dermatitis) is a common allergic skin condition. Get the latest information on causes of eczema and skin rash...
Children’s Health: 11 Causes of Common Skin Rashes
What causes skin rashes in children? See which chemicals in your home could be causing your child's skin rash, irritated skin,...
8 First Aid Kit Essentials for Scrapes, Cuts, Bug Bites, and More in Pictures
Are you always prepared for a first aid crisis? See which basic first aid items to pack to treat minor scrapes, cuts, and stings...
Bandaging Basics in Pictures: From Head to Toe, Burns, Scrapes, and More
Do you know which type of bandage to use with a scrape, poke, blister or burn? Learn the best way to cover or wrap your injury,...
First Aid Quiz – Caring for Cuts, Scrapes, Burns, and Wounds in Pictures
What works for a wound, and what's a myth? Test your first aid knowledge about how to care for scrapes, cuts, and burns and...
How to Get Rid of Hemorrhoids: Types, Causes, and Treatments
Learn how to get rid of hemorrhoids, the difference between internal hemorrhoids and external hemorrhoids, what causes...
Related Disease Conditions
An anal fissure is a small tear or cut in the skin lining of the anus. Pain and/or rectal bleeding during bowel movements are common symptoms of anal fissures. Treatment includes increasing liquid intake, using stool softeners, prescription medications, and surgery.
Burns (First Aid)
Burn types are based on their severity: first-degree burns, second-degree burns, and third-degree burns. First-degree burns are similar to a painful sunburn. The damage is more severe with second-degree burns, leading to blistering and more intense pain. The skin turns white and loses sensation with third degree burns. Burn treatment depends upon the burn location, total burn area, and intensity of the burn.
Eczema is a general term for many types dermatitis (skin inflammation). Atopic dermatitis is the most common of the many types of eczema. Other types of eczema include: contact eczema, allergic contact eczema, seborrheic eczema, nummular eczema, stasis dermatitis, and dyshidrotic eczema.
Hemorrhoids (piles) are swollen veins in the rectum and anus. Causes include pregnancy, obesity, diarrhea, low-fiber diet, and prolonged sitting on the toilet. Treatment varies depending upon the severity of the hemorrhoids. Some treatment options include over-the-counter creams and suppositories, stool softeners, warm sitz baths, and hemorrhoidectomies.
Poison ivy, oak, and sumac contain a substance called urushiol, which causes a rash on people who come in contact with them. Symptoms and signs include a red, swollen, itchy, blistering, bumpy rash. Treatment involves rinsing the exposed area with water, taking antihistamines and over-the-counter pain medications, using topical treatments such as calamine lotion, and applying cool compresses.
Insect Sting Allergies
The majority of stinging insects in the United States are from bees, yellow jackets, hornets, wasps, and fire ants. Severity of reactions to stings varies greatly. Avoidance and prompt treatment are essential. In selected cases, allergy injection therapy is highly effective.
Hives (Urticaria & Angioedema)
Hives, also called urticaria, is a raised, itchy area of skin that is usually a sign of an allergic reaction. The allergy may be to food or medications, but usually the cause of the allergy (the allergen) is unknown.
The word "rash" means an outbreak of red bumps on the body. The way people use this term, "a rash" can refer to many different skin conditions. The most common of these are scaly patches of skin and red, itchy bumps or patches all over the place.
How to Stop Anal Itching
Anal itching is the irritation of the skin at the exit of the rectum, known as the anus, accompanied by the desire to scratch. Causes include everything from irritating foods we eat, to certain diseases, and infections. Treatment options include over-the-counter medications, using moist pads, and gentle cleaning and drying of the anus.
Cold Sores (Nongenital Herpes Simplex Infections)
Herpes simplex infections are common and when they appear around the mouth and lips, people often refer to them as "cold sores" and "fever blisters." Canker sores are different than cold sores. Air droplets can spread the virus, as can direct contact with the fluid from the blisters. Cold sore treatment include over-the-counter medication, as well as prescription medications.
Vaginitis (Inflammation of the Vagina)
Vaginitis refers to inflammation of the vagina. Vaginitis can be caused by infections, menopause, or poor hygiene. Symptoms of vaginitis include vaginal itching, discharge, odor, pain, or discomfort. Treatment for vaginitis depends on the cause. Antibiotics may be necessary for some forms of vaginitis.
Eczema refers to skin inflammation. There are many different types of eczema that produce symptoms and signs that range from oozing blisters to crusty plaques of skin. Treatment varies depending upon the type of eczema the person has.
Bug Bites and Stings
Bug bites and stings have been known to transmit insect-borne illnesses such as West Nile virus, Rocky Mountain spotted fever, and Lyme disease. Though most reactions to insect bites and stings are mild, some reactions may be life-threatening. Preventing bug bites and stings with insect repellant, wearing the proper protective attire, and not wearing heavily scented perfumes when in grassy, wooded, and brushy areas is key.
Sunburn (Sun Poisoning)
Sunburn is caused by overexposure to UV radiation from the sun. UV rays can also damage the eyes. Repeated overexposure to UV rays also increases the risk for scarring, freckles, wrinkles, and dry skin. Symptoms of sunburn include painful, red, tender, and hot skin.The skin may blister, swell, and peel. Sun poisoning (severe sunburn) include nausea, fever, chills, rapid pulse, dizziness and more. Home remedies can help relieve sunburn pain, blisters, and peeling. Severe sunburns may need medical treatment. Sun protection and sunscreen for an person's skin type is recommended to decrease the chance of a severe sunburn and sun poisoning.
Contact dermatitis is a rash that occurs after exposure to an irritant. It can be allergic. Symptoms include a red, elevated rash at the site of contact with the irritating substance. Contact dermatitis treatment may involve: creams, application of cool water compresses, and applying topical steroids.
Is Eczema Contagious?
Eczema is a skin condition characterized by inflamed, rough skin patches that occasionally produce fluid-filled bumps that may ooze. There is no cure for eczema, though eczema may be treated with moisturization, eczema cream, and topical steroids.
Are Cold Sores (Fever Blisters) Contagious?
About 20% of cases of cold sores are caused by herpes simplex virus type 2 (HSV-2), and approximately 80% of cold sores are caused by herpes simplex virus type 1 (HSV-1). Cold sores are transmitted by sharing utensils and razors, kissing, and oral sex. There is no cure for cold sores.
Are Skin Rashes Contagious?
Direct and indirect contact can spread some types of rashes from person to person. Rash treatment depends upon a rash's underlying cause. A rash that sheds large amounts of skin warrants urgent medical attention. Rashes can be either contagious or noncontagious. Noncontagious rashes include seborrheic dermatitis, atopic dermatitis, contact dermatitis, stasis dermatitis, psoriasis, nummular eczema, drug eruptions, hives, heat rash (miliaria), and diaper rash. Rashes usually considered contagious include molluscum contagiosum (viral), impetigo (bacterial), herpes (herpes simplex, types 1 and 2 viruses), rash caused by Neisseria meningitides (N. meningitides) (bacterial), rash and blisters that accompany shingles (herpes zoster virus), ringworm (fungal) infections (tinea), scabies (itch mite), chickenpox (viral), measles and rubella (viral), erythema infectiosum (viral), pityriasis rosea (viral), cellulitis and erysipelas (bacterial), lymphangitis (bacterial, and folliculitis (bacterial).
Treatment & Diagnosis
- Bed Bugs FAQs
- Summer Skin Hazards Pictures FAQs
- Hemorrhoids Piles FAQs
- Eczema FAQs
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Drugs: The Most Common Medication Errors
- Medication Disposal
- Dangers of Mixing Medications
- Drugs: Buying Prescription Drugs Online Safely
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
Prevention & Wellness
Health Solutions From Our Sponsors
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Reference: FDA Prescribing Information