- What is pramoxine-hydrocortisone lotion? How does it work (mechanism of action)?
- What are the side effects of pramoxine-hydrocortisone?
- What is the dosage for pramoxine-hydrocortisone?
- Which drugs or supplements interact with pramoxine-hydrocortisone?
- Is pramoxine-hydrocortisone safe to use if you are pregnant or breastfeeding?
- What else should you know about pramoxine-hydrocortisone?
What is pramoxine-hydrocortisone lotion? How does it work (mechanism of action)?
- Pramoxine-hydrocortisone products are used to treat pain and inflammation caused by various skin conditions. Hydrocortisone is a synthetic (man-made) corticosteroid that is used on the skin (topically). The naturally-occurring corticosteroid is cortisol or hydrocortisone produced by the adrenal gland. Corticosteroids have potent anti-inflammatory actions and also suppress the immune response.
- Pramoxine is a local anesthetic (numbing agent) that provides relief from itching and pain. Local anesthetics are chemicals that interfere with the function of the nerves that sense pain. Pramoxine may be used in persons who are allergic to other local anesthetics such as lidocaine, procaine, or benzocaine.
- The FDA approved hydrocortisone/pramoxine in August 1976.
- Epifoam, Pramosone, Proctofoam HC, Procort, Analpram HC are the brand names for pramoxine-hydrocortisone products.
- Pramoxine-hydrocortisone is not available in generic form.
- You need a prescription for pramoxine-hydrocortisone.
What are the side effects of pramoxine-hydrocortisone?
Common side effects include:
What is the dosage for pramoxine-hydrocortisone?
Hydrocortisone/pramoxine is applied to the affected area as a thin film 3 to 4 times a day depending on the severity of condition.
Which drugs or supplements interact with pramoxine-hydrocortisone?
There are no drug interactions listed for topical hydrocortisone/pramoxine.
Is pramoxine-hydrocortisone safe to use if you are pregnant or breastfeeding?
What else should you know about pramoxine-hydrocortisone?
What preparations of pramoxine-hydrocortisone are available?
- Rectal aerosol foam: 1%/1%
- Cream: 0.5%/1%, 1%/1%, and 2.5%/1%
- Lotion: 1%/1% and 2.5%/1%
How should I keep pramoxine-hydrocortisone stored?
- Hydrocortisone/pramoxine cream and lotion should be stored at room temperature between 15 C and 30 C (59 F and 86 F).
- The aerosol foam is stored at room temperature, between 20 C and 25 C (68 F and 77 F).
Hydrocortisone and pramoxine (Epifoam, Pramosone, Proctofoam HC, Procort, Analpram HC) is a prescription medication used to treat inflammation and itching caused by skin conditions; and to relieve the pain, inflammation, and burning caused by hemorrhoids. Side effects, drug interactions, warnings, dosing, and pregnancy and breastfeeding information should be provided prior to using any drug or supplement.
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Related Disease Conditions
Burns (First Aid)
Burn types are based on their severity: first-degree burns, second-degree burns, and third-degree burns. First-degree burns are similar to a painful sunburn. The damage is more severe with second-degree burns, leading to blistering and more intense pain. The skin turns white and loses sensation with third-degree burns. Burn treatment depends upon the burn location, total burn area, and intensity of the burn.
Cuts, Scrapes, and Puncture Wounds
Cuts, scrapes, and puncture wounds are common, and most people will experience one of these in their lifetime. Evaluating the injury, and thoroughly cleaning the injury is important. Some injuries should be evaluated by a doctor, and a tetanus shot may be necessary. Treatment will depend upon the severity of the injury.
Eczema is a general term for many types dermatitis (skin inflammation). Atopic dermatitis is the most common of the many types of eczema. Other types of eczema include: contact eczema, allergic contact eczema, seborrheic eczema, nummular eczema, stasis dermatitis, and dyshidrotic eczema.
Hemorrhoids (piles) are swollen veins in the rectum and anus. Causes include pregnancy, obesity, diarrhea, low-fiber diet, and prolonged sitting on the toilet. Treatment varies depending upon the severity of the hemorrhoids. Some treatment options include over-the-counter creams and suppositories, stool softeners, warm sitz baths, and hemorrhoidectomies.
The word "rash" means an outbreak of red bumps on the body. The way people use this term, "a rash" can refer to many different skin conditions. The most common of these are scaly patches of skin and red, itchy bumps or patches all over the place.
How to Stop Anal Itching
Anal itching is the irritation of the skin at the exit of the rectum, known as the anus, accompanied by the desire to scratch. Causes include everything from irritating foods we eat, to certain diseases, and infections. Treatment options include over-the-counter medications, using moist pads, and gentle cleaning and drying of the anus.
Itch (Itching or Pruritus)
Itching can be a common problem. Itches can be localized or generalized. There are many causes of itching to include: infection (jock itch, vaginal itch), disease (hyperthyroidism, liver or kidney), reactions to drugs, and skin infestations (pubic or body lice). Treatment for itching varies depending on the cause of the itch.
Eczema refers to skin inflammation. There are many different types of eczema that produce symptoms and signs that range from oozing blisters to crusty plaques of skin. Treatment varies depending upon the type of eczema the person has.
Dry skin (xeroderma) may be caused by external factors, like cold temperatures, low humidity, harsh soaps, and certain medications, or internal factors, such as thyroid disease, diabetes, psoriasis, or Sjogren's syndrome. Symptoms and signs of dry skin include itching and red, cracked or flaky skin. The main treatment for dry skin is frequent, daily lubrication of the skin.
Is Eczema Contagious?
Eczema is a skin condition characterized by inflamed, rough skin patches that occasionally produce fluid-filled bumps that may ooze. There is no cure for eczema, though eczema may be treated with moisturization, eczema cream, and topical steroids.
Are Skin Rashes Contagious?
Direct and indirect contact can spread some types of rashes from person to person. Rash treatment depends upon a rash's underlying cause. A rash that sheds large amounts of skin warrants urgent medical attention. Rashes can be either contagious or noncontagious. Noncontagious rashes include seborrheic dermatitis, atopic dermatitis, contact dermatitis, stasis dermatitis, psoriasis, nummular eczema, drug eruptions, hives, heat rash (miliaria), and diaper rash. Rashes usually considered contagious include molluscum contagiosum (viral), impetigo (bacterial), herpes (herpes simplex, types 1 and 2 viruses), rash caused by Neisseria meningitides (N. meningitides) (bacterial), rash and blisters that accompany shingles (herpes zoster virus), ringworm (fungal) infections (tinea), scabies (itch mite), chickenpox (viral), measles and rubella (viral), erythema infectiosum (viral), pityriasis rosea (viral), cellulitis and erysipelas (bacterial), lymphangitis (bacterial, and folliculitis (bacterial).
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