- What is pramoxine-hydrocortisone lotion? How does it work (mechanism of action)?
- What are the side effects of pramoxine-hydrocortisone?
- What is the dosage for pramoxine-hydrocortisone?
- Which drugs or supplements interact with pramoxine-hydrocortisone?
- Is pramoxine-hydrocortisone safe to use if you are pregnant or breastfeeding?
- What else should you know about pramoxine-hydrocortisone?
What is pramoxine-hydrocortisone lotion? How does it work (mechanism of action)?
- Pramoxine-hydrocortisone products are used to treat pain and inflammation caused by various skin conditions. Hydrocortisone is a synthetic (man-made) corticosteroid that is used on the skin (topically). The naturally-occurring corticosteroid is cortisol or hydrocortisone produced by the adrenal gland. Corticosteroids have potent anti-inflammatory actions and also suppress the immune response.
- Pramoxine is a local anesthetic (numbing agent) that provides relief from itching and pain. Local anesthetics are chemicals that interfere with the function of the nerves that sense pain. Pramoxine may be used in persons who are allergic to other local anesthetics such as lidocaine, procaine, or benzocaine.
- The FDA approved hydrocortisone/pramoxine in August 1976.
- Epifoam, Pramosone, Proctofoam HC, Procort, Analpram HC are the brand names for pramoxine-hydrocortisone products.
- Pramoxine-hydrocortisone is not available in generic form.
- You need a prescription for pramoxine-hydrocortisone.
What are the side effects of pramoxine-hydrocortisone?
Common side effects include:
What is the dosage for pramoxine-hydrocortisone?
Hydrocortisone/pramoxine is applied to the affected area as a thin film 3 to 4 times a day depending on the severity of condition.
Which drugs or supplements interact with pramoxine-hydrocortisone?
There are no drug interactions listed for topical hydrocortisone/pramoxine.
Is pramoxine-hydrocortisone safe to use if you are pregnant or breastfeeding?
What else should you know about pramoxine-hydrocortisone?
What preparations of pramoxine-hydrocortisone are available?
- Rectal aerosol foam: 1%/1%
- Cream: 0.5%/1%, 1%/1%, and 2.5%/1%
- Lotion: 1%/1% and 2.5%/1%
How should I keep pramoxine-hydrocortisone stored?
- Hydrocortisone/pramoxine cream and lotion should be stored at room temperature between 15 C and 30 C (59 F and 86 F).
- The aerosol foam is stored at room temperature, between 20 C and 25 C (68 F and 77 F).
IMAGESBrowse our medical image collection of allergic skin disorders such as psoriasis and dermatitis and more caused by allergies See Images
Hydrocortisone and pramoxine (Epifoam, Pramosone, Proctofoam HC, Procort, Analpram HC) is a prescription medication used to treat inflammation and itching caused by skin conditions; and to relieve the pain, inflammation, and burning caused by hemorrhoids. Side effects, drug interactions, warnings, dosing, and pregnancy and breastfeeding information should be provided prior to using any drug or supplement.
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Anal itching is the irritation of the skin at the exit of the rectum, known as the anus, accompanied by the desire to scratch. Causes include everything from irritating foods we eat, to certain diseases, and infections. Treatment options include over-the-counter medications, using moist pads, and gentle cleaning and drying of the anus.
Hemorrhoids (Internal and External)
Hemorrhoids (piles) are swollen veins in the rectum and anus. Causes include pregnancy, obesity, diarrhea, low-fiber diet, and prolonged sitting on the toilet. Treatment varies depending upon the severity of the hemorrhoids. Some treatment options include over-the-counter creams and suppositories, stool softeners, warm sitz baths, and hemorrhoidectomies.
The word "rash" means an outbreak of red bumps on the body. The way people use this term, "a rash" can refer to many different skin conditions. The most common of these are scaly patches of skin and red, itchy bumps or patches all over the place.
Itch (Itching or Pruritus)
Itching can be a common problem. Itches can be localized or generalized. There are many causes of itching including infection (jock itch, vaginal itch), disease (hyperthyroidism, liver or kidney), reactions to drugs, and skin infestations (pubic or body lice). Treatment for itching varies depending on the cause of the itch.
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Dry skin (xeroderma) may be caused by external factors, like cold temperatures, low humidity, harsh soaps, and certain medications, or internal factors, such as thyroid disease, diabetes, psoriasis, or Sjogren's syndrome. Symptoms and signs of dry skin include itching and red, cracked, or flaky skin. The main treatment for dry skin is frequent, daily lubrication of the skin.
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Burns (First Aid)
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