Polyarteritis Nodosa (PAN): Symptoms & Signs

Medically Reviewed on 12/13/2019

Polyarteritis nodosa (PAN) is a condition caused by an autoimmune reaction, in which the body's immune system attacks its own tissues. In polyarteritis nodosa, the abnormal immune reaction is directed against the blood vessels in the body and can occur in any part of the body. Parts of the body often affected include the nerves, heart, joints, and digestive tract.

Signs and symptoms associated with polyarteritis nodosa include

Other symptoms and signs can include

Cause of polyarteritis nodosa

The cause of PAN is unknown.

Other polyarteritis nodosa (pan) symptoms and signs

Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.