Is Polyarteritis Nodosa Different from Lupus?

Last Editorial Review: 6/21/2017

Ask the experts

I have been diagnosed with polyarteritis nodosa (PAN). How does PAN differ from lupus?

Doctor's response

Polyarteritis nodosa is a type of inflammation of the blood vessels (vasculitis) that affects medium- and large-sized arteries. Depending on which blood vessels are involved and specifically the tissues they supply, injury can occur to internal organs, such as the kidneys or bowel.

Systemic lupus erythematosus (SLE) is an autoimmune disease that can cause inflammation of many tissues of the body, including the skin, joints, lungs, heart, nervous system, and kidneys. SLE may or may not cause vasculitis.

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Medically reviewed by John A. Daller, MD; American Board of Surgery with subspecialty certification in surgical critical care


"Clinical manifestations and diagnosis of polyarteritis nodosa in adults"