- What is pneumococcal vaccine-injection, and how does it work (mechanism of action)?
- What brand names are available for pneumococcal vaccine-injection?
- Is pneumococcal vaccine-injection available as a generic drug?
- Do I need a prescription for pneumococcal vaccine-injection?
- What are the side effects of pneumococcal vaccine-injection?
- What is the dosage for pneumococcal vaccine-injection?
- Which drugs or supplements interact with pneumococcal vaccine-injection?
- Is pneumococcal vaccine-injection safe to take if I'm pregnant or breastfeeding?
- What else should I know about pneumococcal vaccine-injection?
What is pneumococcal vaccine-injection, and how does it work (mechanism of action)?
Pneumococcal vaccine is used for prevention of pneumonia. This pneumococcal vaccine contains chemicals (polysaccharides) extracted from 23 types of Streptococcus pneumonia bacteria. Upon injecting pneumococcal vaccine, our body recognizes these chemical as foreign and produces antibodies to destroy the chemicals. Antibodies are blood protein that help the body fight infection and destroy other harmful substances. Once produced, these antibodies destroy injected Streptococcus pneumonia chemicals. However, the antibodies remain active in the body and can detect the same chemicals from live Streptococcus pneumonia in the future. If a vaccinated person comes in contact with Streptococcus pneumonia the antibodies will destroy the bacteria and prevent pneumonia or reduce its severity. The FDA approved pneumococcal vaccine polyvalent in June 1983.
This vaccine should not be confused with pneumococcal conjugate vaccine (PCV13) used in special conditions (children <5 years old, for example) because often in the medical literature the non-specific term "pneumococcal vaccine" is used.
What are the side effects of pneumococcal vaccine-injection?
Common side effects of pneumococcal vaccine are:
- Injection site pain
Other side effects include:
Severe allergic reactions may occur.
What is the dosage for pneumococcal vaccine-injection?
The recommended dose is 0.5 ml injected intramuscularly or subcutaneously. Routine revaccination is not recommended unless patients' previous vaccine history is unknown.
Pneumococcal vaccine (PCV 23) is not recommended for children under the age of 2.
Which drugs or supplements interact with pneumococcal vaccine-injection?
Administration of pneumococcal vaccine is not recommended at the same time as zoster vaccine live (Zostavax). When they are given concurrently, pneumococcal vaccine reduces the response of zoster vaccine compared to those who received both vaccines 4 weeks apart.
Medications such as cyclosporine (Sandimmune, Neoral) and tacrolimus (Prograf) that weaken the immune system should not be used with pneumococcal vaccine. Cyclosporine and tacrolimus reduce the effects of pneumococcal vaccine; therefore, such patients must be evaluated before recommending pneumococcal vaccine.
Is pneumococcal vaccine-injection safe to take if I'm pregnant or breastfeeding?
It is not known whether pneumococcal vaccine enters breast milk.
What else should I know about pneumococcal vaccine-injection?
What preparations of pneumococcal vaccine-injection are available?
- Pneumococcal vaccine is a sterile, liquid vaccine for intramuscular or subcutaneous injections only.
- Pneumococcal vaccines are available in 5-dose vials.
- They are also available as a pack of 10 single dose vials and 10 single-dose pre-filled syringes.
- Each 0.5 ml dose contains 25 mcg polysaccharide of each pneumococcal type.
How should I keep pneumococcal vaccine-injection stored?
Pneumococcal vaccine should be refrigerated between 2 C to 8 C (36 F to 46 F).
Pneumococcal polyvalent vaccine (Pneumovax 23, Pnu-Imune 23) is a vaccine used for individuals over the age of 50 years and children age 2 years or older who are at an increased risk for pneumococcal disease, and have no complicating medical issues. Side effects, drug interactions, dosing and storage information, and pregnancy safety information is provided.
Multimedia: Slideshows, Images & Quizzes
Meningitis Quiz: Test Your Infectious Disease IQ
What is meningitis and what causes it? Take our Meningitis Quiz to learn the causes, symptoms, treatments, and complications of...
Do I Have Pneumonia? Symptoms & Signs
Pneumonia can be deadly. Take the Pneumonia Quiz on MedicineNet to learn more about this highly contagious, infectious disease....
Related Disease Conditions
Diabetes (Type 1 and Type 2)
Diabetes is a chronic condition characterized by high levels of sugar (glucose) in the blood. The two types of diabetes are...
Pneumonia is inflammation of the lungs caused by fungi, bacteria, or viruses. Symptoms and signs include cough, fever, shortness...
Encephalitis is a brain inflammation that causes sudden fever, vomiting, headache, light sensitivity, stiff neck and back,...
Treatment & Diagnosis
Medications & Supplements
Prevention & Wellness
Daily Health News
Subscribe to MedicineNet's General Health Newsletter
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Top pneumococcal vaccine-injection Related Articles
Diabetes MellitusDiabetes is a chronic condition characterized by high levels of sugar (glucose) in the blood. The two types of diabetes are referred to as type 1 (insulin dependent) and type 2 (non-insulin dependent). Symptoms of diabetes include increased urine output, thirst, hunger, and fatigue. Treatment of diabetes depends on the type.
Encephalitis and MeningitisEncephalitis is a brain inflammation that causes sudden fever, vomiting, headache, light sensitivity, stiff neck and back, drowsiness, and irritability. Meningitis is an infection that causes inflammation of the meninges that surround the brain and spinal cord. Symptoms of meningitis include high fever, headache, nausea, vomiting, and stiff neck.
Flu VaccinationEvery year in the United States, on average, 5%-20% of the population gets the flu, more than 200,000 people are hospitalized from flu complications, and about 36,000 people die from flu. The flu is highly infectious and is a serious viral respiratory infection. Flu vaccine is an inactivated vaccine, meaning that it contains killed influenza virus. Anyone who wishes to reduce their risk of getting the flu can be vaccinated, however the U.S. Centers for Disease Control and Prevention recommends that people who are at risk for serious complications from the flu be vaccinated each year.
ImmunizationsImmunizations can prevent many diseases nowadays. It's important to follow the vaccination guidelines recommended on the CDC's vaccination schedule for adults and adolescents in order to stay informed about new vaccines and to learn how often and when the vaccines should be administered.
Meningitis QuizWhat is meningitis and what causes it? Take our Meningitis Quiz to learn the causes, symptoms, treatments, and complications of this potentially life-threatening disease.
norfloxacin-oralNorfloxacin (Noroxin) is an antibiotic prescribed to treat a variety of infections such as UTIs, gonorrhea, E. coli, and others. Side effects, drug interactions, dosage, storage, and pregnancy information should be reviewed prior to taking this medication.
Pneumococcal VaccinationPneumococcal vaccination prevents one of the most common and severe forms of pneumonia. It is usually given only once in a lifetime, usually after the age of 55, to someone with ongoing lung problems (such as chronic obstructive pulmonary disease (COPD) or asthma) or other chronic diseases (including those involving the heart and kidneys).
Pneumonia FactsPneumonia is inflammation of the lungs caused by fungi, bacteria, or viruses. Symptoms and signs include cough, fever, shortness of breath, and chills. Antibiotics treat pneumonia, and the choice of the antibiotic depends upon the cause of the infection.
Do I Have Pneumonia?Pneumonia can be deadly. Take the Pneumonia Quiz on MedicineNet to learn more about this highly contagious, infectious disease.
Vaccination FAQsVaccinations increase our ability to fight diseases that may be contagious or even fatal. Immunity occurs by getting the disease or through the use of a vaccine. There are two types of vaccine: inactivated vaccines and vaccines made from live, weakened viruses.