Pleurodesis: A procedure that causes the membranes around the lungs to stick together and prevents the buildup of fluid in the space between the membranes (pleural space). Pleurodesis is done in cases of severe recurrent pleural effusions (outpourings of fluid around the lungs) to prevent the reaccumulation of the fluid. During pleurodesis, an irritant is instilled inside the pleural space in order to create inflammation that tacks the two pleura together. This procedure thereby permanently obliterates the space between the pleura and prevents the reaccumulation of fluid.
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