Pigmented villonodular synovitis (PVNS) is a condition characterized by thickening and overgrowth of the normal lining tissue of joints (known as synovium). PVNS is not a cancer and does not spread outside the joint. It mostly affects the knee joint but can involve other joints. Pigmented villonodular synovitis is a progressive condition that worsens over time.
Signs and symptoms associated with pigmented villonodular synovitis include joint pain, swelling of the joint, and difficulty moving the affected joint, possibly leading to joint instability or joint stiffness. Typically, PVNS involves only one joint. Other symptoms can include locking or catching of the affected joint. The symptoms may come and go over time.
Cause of pigmented villonodular synovitis
The cause of PVNS is unknown.
Other pigmented villonodular synovitis symptoms and sign
- Difficulty Moving the Affected Joint
- Joint Instability
- Joint Pain
- Joint Stiffness
- Limitation of Movement
- Locking of the Joint
- Swollen Joints
Main Article on Pigmented Villonodular Synovitis Symptoms and Sign
SLIDESHOW
What Is Rheumatoid Arthritis (RA)? Symptoms, Treatment, Diagnosis See SlideshowPictures, Images, Illustrations & Quizzes
-
Arthritis: 16 Bad Habits That Cause Joint Pain
Being overweight, wearing uncomfortable shoes, or carrying a heavy purse can make joint pain and arthritis symptoms worse. Some...
-
Arthritis: Causes and Treatment for Joint Stiffness and Pain
Arthritis and injuries can leave your joints swollen, tender, and damaged. Discover treatments for morning stiffness, sore...
-
Exercises for Knee Osteoarthritis and Joint Pain
Learn about osteoarthritis and exercises that relieve knee osteoarthritis pain, stiffness and strengthen the knee joint and...
-
Pain Management: Knee Pain Dos and Don'ts
Your knees go through a lot in the course of a day, and sometimes they can run into trouble. Here are a few things you can do...
-
Picture of Knee Joint
The knee joint has three parts. See a picture of Knee Joint and learn more about the health topic.
-
Tips for Healthy Joints: Exercise, Nutrition, & More
Dealing with joint pain and arthritis? Learn why weight matters--and why NOT to stretch before exercise. See these solutions for...
From 
Arthritis Resources
Featured Centers
Health Solutions From Our Sponsors
Subscribe to MedicineNet's Arthritis Newsletter
By clicking "Submit," I agree to the MedicineNet Terms and Conditions and Privacy Policy. I also agree to receive emails from MedicineNet and I understand that I may opt out of MedicineNet subscriptions at any time.