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What is Physostigmine, and how does it work?
Physostigmine Salicylate Injection is an antidote used to reverse the effect of drugs that cause anticholinergic syndrome.
What are the side effects of Physostigmine?
Common side effects of physostigmine salicylate include:
What is the dosage for Physostigmine?
Past Anesthesia Care
- 0.5 to 1.0 mg intramuscularly or intravenously. Intravenous administration should be at a slow controlled rate of no more than 1 mg per minute.
- Dosage may be repeated at intervals of 10 to 30 minutes if desired patient response is not obtained.
Overdosage Of Drugs That Cause Anticholinergic
- 2.0 mg intramuscularly or intravenously at slow controlled rate (see above).
- Dosage may be repeated if life threatening signs, such as arrhythmia, convulsions or coma occurs.
- Recommended dosage is 0.02 mg/kg; intramuscularly or by slow intravenous injection, no more than 0.5 mg per minute.
- If the toxic effects persist, and there is no sign of cholinergic effects, the dosage may be repeated at 5 to 10 minute intervals until a therapeutic effect is obtained or a maximum of 2 mg dosage is attained.
Physostigmine Salicylate Injection is an antidote used to reverse the effect of drugs that cause anticholinergic syndrome. Common side effects of physostigmine salicylate include nausea, vomiting, salivation, stomach cramps, diarrhea, and excessive sweating.
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Related Disease Conditions
Digestive Diseases: Food Poisoning
Second Source WebMD Medical Reference
Second Source article from Government
Food poisoning is common, but can also be life threatening. The symptoms for food poisoning are fever, abdominal pain, headache, diarrhea, nausea and vomiting. Food poisoning has many causes, for example, chemicals (from toxic fish or plants) and bacteria (Staphylococcus aureus or Salmonella). Treatment of food poisoning depends upon the cause.
Radon (A Citizen's Guide to Radon)
Radon is a radioactive gas that has been confirmed to cause cancers. About 21,000 individuals die each year due to radon exposure. Radon can be found in the ground, water supply, and the air you breathe. It is found in schools, homes, offices, and other buildings. You can purchase a Radon Test Kit and have the sample sent to the state radon office. Research has shown that the risk of lung cancer from breathing radon in air is much greater than the risk of stomach cancer from swallowing water with radon in it. The EPA offers a Consumers Guide to Radon Reduction so you can take action to reduce radon levels in your home, school, or office. Scientists are more certain about radon risks than from most other cancer-causing substances.
Lead-based paint and lead contaminated dust are the main sources of exposure for lead in U.S. children. Lead-based paints were banned for use in housing in 1978. All houses built before 1978 are likely to contain some lead-based paint. However, it is the deterioration of this paint that causes a problem. Approximately 24 million housing units have deteriorated leaded paint and elevated levels of lead-contaminated house dust. More than 4 million of these dwellings are homes to one or more young children. Lead poisoning is entirely preventable. The key is stopping children from coming into contact with lead and treating children who have been poisoned by lead.
Salmonella infection (salmonellosis) is typically caused by the consumption of contaminated foods. Symptoms of salmonellosis include fever, vomiting, diarrhea, and abdominal pain. Salmonellosis typically resolves on its own in four to seven days. It's important to increase one's fluid intake to compensate for the fluid lost by vomiting and/or diarrhea.
Ricin is a biological toxin that can be made from processing castor beans. The length of time it takes for the poison to begin working depends on if you inhaled or ingested it, or if your skin and eyes were exposed. However, generally symptoms begin a few hours after poisoning; typically less than 10. You can die from ricin poisoning between 36 and 72 hours after exposure. Symptoms of ricin poisoning include: Fever Cough Nausea Low blood pressure Diarrhea Seizures Blood in the urine As there is no antidote, treatment focuses on minimizing the effects of poisoning.
Sunburn (Sun Poisoning)
Sunburn is caused by overexposure to UV radiation from the sun. UV rays can also damage the eyes. Repeated overexposure to UV rays also increases the risk for scarring, freckles, wrinkles, and dry skin. Symptoms of sunburn include painful, red, tender, and hot skin.The skin may blister, swell, and peel. Sun poisoning (severe sunburn) include nausea, fever, chills, rapid pulse, dizziness and more. Home remedies can help relieve sunburn pain, blisters, and peeling. Severe sunburns may need medical treatment. Sun protection and sunscreen for an person's skin type is recommended to decrease the chance of a severe sunburn and sun poisoning.
Mercury is a naturally occurring element found in water, soil, and the air. Mercury also is contained in some fish, some of the products we use in the home, school, or dentist. Mercury poisoning can cause cognitive problems, dermatitis, tremor and other symptoms. Information about sources of mercury exposure, potential health effects, symptoms of exposure, fish that may contain mercury, consumer products that contain mercury, and ways to reduce your exposure to mercury is important for the health of you, and your family.
Arsenic comes in two forms, inorganic and organic. Organic arsenic poisoning is usually not poisonous to humans; however, inorganic arsenic in large enough amounts can lead to shock and death. Symptoms of arsenic poisoning include nausea, abdominal pain, diarrhea, dehydration, dark urine, vertigo, delirium, shock, and death. Treatment for arsenic poisoning includes Hemodialysis and a variety of drugs.
Ciguatera poisoning is a type of food poisoning caused by the ciguatera toxin found in a variety of large reef fish found between the Tropic of Cancer and the Tropic of Capricorn. Symptoms of ciguatera poisoning include diarrhea, nausea, vomiting, abdominal pain, dizziness, vertigo, numbness, tingling, and muscle pain. Ciguatera poisoning requires medical treatment.
Stomach Flu vs. Food Poisoning
The stomach flu (viral gastroenteritis) and food poisoning are not the same infections. However, they do have a few similar symptoms, for example: Nausea Vomiting Diarrhea Fever Abdominal (stomach) pain and cramping. Symptoms and signs of food poisoning show up earlier (2 hours up to a couple of days) in comparison to the stomach flu in which symptoms may take 4 hours up to 48 hours (2 days) before symptoms begin. Medical treatment for the stomach flu and food poisoning generally is not necessary. A bland diet, drinking plenty of fluids, and rest may be the only treatment necessary.
When Stomach Pain Is and Is Not an Emergency
Most stomach pains are harmless. They may be caused by overeating, gas, or indigestion. If your pain is short term, goes away after passing gases or stools, and with over-the-counter products (laxative and antacids) or home remedies, there is nothing to worry about. If your belly pain is severe, doesn't go away, or keeps coming back, talk to your doctor.
Is It a Stomach Virus or Food Poisoning?
A stomach virus is also called stomach flu or gastroenteritis. It is a viral infection that infects the tummy and the gut. Food poisoning is also often called gastroenteritis and may present symptoms like stomach virus/stomach flu. However, food poisoning is caused by consuming food or drinks that may be contaminated with bacteria.
What Happens When You Get Mercury Poisoning?
Exposure to high levels of mercury can harm the brain, heart, kidneys, lungs, and immune system of people of all ages. Very young children and unborn are the most susceptible to the effects of mercury. Although mercury is known to cause tumors in rats in the laboratory, there is insufficient proof to link mercury with cancers in humans.
Can Ricin Poisoning Cause Death?
Effects of ricin poisoning depend on whether ricin was inhaled, ingested, or injected. Ricin poisoning can eventually lead to multiple organ failure, leading to death within 36-72 hours of exposure, depending on the dosage of ricin and mode of exposure. There is no antidote for ricin; hence, ricin poisoning is mainly treated symptomatically with supportive medical care to reduce the effects of poisoning.
What Does Lead Poisoning Do To Adults?
Lead is a naturally occurring toxic metal found in the earth’s crust. Excess lead buildup in the body can cause lead poisoning. Although lead poisoning primarily affects children, it can also prove to be dangerous in adults.
How Long Does It Take to Get Lead Poisoning?
Lead poisoning usually takes months or years of exposure to a small amount of lead at home, work or daycare. When exposed to large amounts of lead, it can quickly lead to lead poisoning (acute poisoning).
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