Peripheral neuropathy is a problem with the functioning of the nerves outside of the spinal cord. Symptoms may include numbness, weakness, burning pain (especially at night), and loss of reflexes. Possible causes may include carpel tunnel syndrome, shingles, vitamin or nutritional deficiencies, and illnesses like diabetes, syphilis, AIDS, and kidney failure. Peripheral neuropathy is diagnosed with exams and tests. Treatment for the condition depends on the cause. Usually, the prognosis for peripheral neuropathy is good if the cause can be successfully treated or prevented. Read more: Peripheral Neuropathy Article
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Type 2 Diabetes Diagnosis, Treatment, Medication
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Rheumatoid Arthritis (RA) Symptoms & Treatment
What is rheumatoid arthritis (RA)? Learn about juvenile rheumatoid arthritis. Discover rheumatoid arthritis (RA) symptoms,...
Erectile Dysfunction (ED) Causes and Treatment
Having erection problems? What is erectile dysfunction (ED)? Learn about erectile dysfunction causes and treatments such as drugs...
Pain Management: Surprising Causes of Pain
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Common Causes of Foot Pain
Learn about common causes of foot pain such as bunions, corns, athlete's foot, plantar warts and more. Get the latest information...
Type 1 Diabetes: What Are The Symptoms?
What is type 1 diabetes? Is there a cure for type 1 diabetes? Learn about type 1 diabetes symptoms, warning signs, causes, and...
Type 2 Diabetes: Test Your Medical IQ
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Type 1 Diabetes Quiz: Test Your Medical IQ
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Erectile Dysfunction (Impotence) Quiz: Causes & Treatment
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Diabetes Quiz: Test Your Medical IQ
Take the Diabetes Quiz and learn the causes, signs, symptoms, and types of this growing epidemic. What does diabetes have to do...
Crohn's Disease Quiz
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Kidney Disease Quiz: Test Your Medical IQ
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Pain Quiz: Test Your IQ of Pain
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Systemic Lupus Erythematosus Quiz: Test Your SLE IQ
This Lupus Quiz covers causes, signs, symptoms, facts, and treatments for this inflammatory autoimmune disease.
Crohn's Disease: Symptoms, Causes, Diet
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Picture of Lupus
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Acute systemic lupus erythematosus. See a picture of Acute Systemic Lupus and learn more about the health topic.
HIV AIDS Facts: Symptoms and Treatments
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Nerve Pain: Symptoms, Causes, and Treatment Options
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Lupus Symptoms, Rash, and Treatment
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Lyme Disease Symptoms, Rash, Treatments
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How Diabetes Can Affect Your Feet
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Related Disease Conditions
Kidney (Renal) Failure
Kidney failure can occur from an acute event or a chronic condition or disease. Prerenal kidney failure is caused by blood loss, dehydration, or medication. Some of the renal causes of kidney failure include sepsis, medications, rhabdomyolysis, multiple myeloma, and acute glomerulonephritis. Post renal causes of kidney failure include bladder obstruction, prostate problems, tumors, or kidney stones.Treatment options included diet, medications, or dialysis.
Diabetes (Type 1 and Type 2)
Diabetes is a chronic condition characterized by high levels of sugar (glucose) in the blood. The two types of diabetes are referred to as type 1 (insulin dependent) and type 2 (non-insulin dependent). Symptoms of diabetes include increased urine output, thirst, hunger, and fatigue. Treatment of diabetes depends on the type.
Cancer is a disease caused by an abnormal growth of cells, also called malignancy. It is a group of 100 different diseases, and is not contagious. Cancer can be treated through chemotherapy, a treatment of drugs that destroy cancer cells.
Genetic Diseases (Disorder Definition, Types, and Examples)
The definition of a genetic disease is a disorder or condition caused by abnormalities in a person's genome. Some types of genetic inheritance include single inheritance, including cystic fibrosis, sickle cell anemia, Marfan syndrome, and hemochromatosis. Other types of genetic diseases include multifactorial inheritance. Still other types of genetic diseases include chromosome abnormalities (for example, Turner syndrome, and Klinefelter syndrome), and mitochondrial inheritance (for example, epilepsy and dementia).
A broken foot is a common injury. There are 26 bones in the foot, and these bones can be broken (fractured) in a variety of ways. Signs and symptoms of a broken bone in the foot are pain, swelling, redness, bruising, and limping because the person is not able to walk on the affected foot. You can tell if you have a broken foot by medical examination that includes imaging studies. The healing and recovery time for a broken bone in the foot depends upon the type of fracture and the bones broken.
Sexual Problems in Men
Male sexual dysfunction can be caused by physical or psychological problems. Common sexual problems in men include erectile dysfunction (impotence or ED), premature ejaculation, and loss of libido. Treatment for sexual dysfunction in men may involve medication, hormone therapy, psychological therapy, and the use of mechanical aids.
Pernicious anemia is a blood disorder in which the body does not make enough red blood cells due to a lack of vitamin B12 in the blood. Pernicious anemia can develop from a lack of a protein that helps the body absorb vitamin B12, not getting enough B12 in the diet, and certain intestinal conditions that interfere with the absorption of vitamin B12 such as Crohn's disease, celiac sprue, or ulcerative colitis. There is no cure for pernicious anemia, thus treatment is life-long.
Shingles, or herpes zoster, is a painful rash caused by the varicella zoster virus. Other shingles symptoms include headache, fever, nausea, and body aches. Treatment focuses on pain management and shortening the duration of the illness with antiviral medications.
Rheumatoid Arthritis (RA)
Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints, the tissue around the joints, as well as other organs in the body. Because it can affect multiple other organs of the body, rheumatoid arthritis is referred to as a systemic illness and is sometimes called rheumatoid disease. The 16 characteristic early RA signs and symptoms include the following. Anemia Both sides of the body affected (symmetric) Depression Fatigue Fever Joint deformity Joint pain Joint redness Joint stiffness Joint swelling Joint tenderness Joint warmth Limping Loss of joint function Loss of joint range of motion Many joints affected (polyarthritis)
Restless Leg Syndrome
Restless leg syndrome (RLS) is a common cause for painful legs that typically eases with motion, and becomes worse and more noticeable at rest. This characteristic nighttime worsening can frequently lead to insomnia. Treatment of the symptoms of restless leg syndrome is generally with medication as well as treating any underlying condition causing restless leg syndrome.
Type 1 vs Type 2 Diabetes (Similarities and Differences)
Diabetes mellitus is a metabolic condition in which a person's blood sugar (glucose) levels are too high. Over 29.1 million children and adults in the US have diabetes. Of that, 8.1 million people have diabetes and don't even know it. Type 1 diabetes (insulin-dependent, juvenile) is caused by a problem with insulin production by the pancreas. Type 2 diabetes (non-insulin dependent) is caused by: Eating a lot of foods and drinking beverages with simple carbohydrates (pizza, white breads, pastas, cereals, pastries, etc.) and simple sugars (donuts, candy, etc.) Consuming too many products with artificial sweeteners (We found out that they are bad for us!) Lack of activity Exercise Stress Genetics While the signs and symptoms of both types of diabetes are the same, which include: Increased urination Increased hunger Increased thirst Unexplained weight loss. However, the treatments are different. Type 1 diabetes is insulin dependent, which means a person with this type of diabetes requires treatment with insulin. People with type 2 diabetes require medication, lifestyle changes like eating a healthy diet, and getting regular exercise.
Diabetes Treatment (Type 1 and Type 2 Medications and Diet)
The major goal in treating diabetes is controlling elevated blood sugar without causing abnormally low levels of blood sugar. Type 1 diabetes is treated with: insulin, exercise, and a diabetic diet. Type 2 diabetes is first treated with: weight reduction, a diabetic diet, and exercise. When these measures fail to control the elevated blood sugar, oral medications are used. If oral medications are still insufficient, insulin medications are considered.
Pinched Nerve (Symptoms, Locations, Causes, Treatment, and Prognosis)
A pinched nerve causes pain, numbness, or tingling in the affected area due to pressure on a nerve. Carpal tunnel and sciatica are two examples of conditions caused by a pinched nerve. A pinched nerve is diagnosed by taking a patient history and performing a physical examination. Electromyography may be performed. Treatment for a pinched nerve depends on the underlying cause.
Crohn's disease is a chronic inflammatory disease, primarily involving the small and large intestine, but which can affect other parts of the digestive system as well. Abdominal pain, diarrhea, vomiting, fever, and weight loss are common symptoms.
Lupus (Systemic Lupus Erythematosus or SLE)
Systemic lupus erythematosus is a condition characterized by chronic inflammation of body tissues caused by autoimmune disease. Lupus can cause disease of the skin, heart, lungs, kidneys, joints, and nervous system. When only the skin is involved, the condition is called discoid lupus. When internal organs are involved, the condition is called systemic lupus erythematosus (SLE).
Pain management and treatment can be simple or complex, according to its cause. There are two basic types of pain, nociceptive pain and neuropathic pain. Some causes of neuropathic pain include: complex regional pain syndrome, interstitial cystitis, and irritable bowel syndrome. There are a variety of methods to treat chronic pain, which are dependant on the type of pain experienced.
Carpal Tunnel Syndrome
Carpal tunnel syndrome is a condition in which irritation of the wrist's median nerve causes tingling and numbness of the thumb, index, and the middle fingers. Treatment of carpal tunnel syndrome depends on the severity of the symptoms and the nature of any disease that might be causing the symptoms.
Type 2 Diabetes
Type 2 diabetes is a chronic condition that may be reversible with diet and lifestyle changes. Symptoms include excessive thirst, frequent urination, weight loss, fatigue, and an unusual odor to your urine. Most people don't know they have type 2 diabetes until they have a routine blood test. Treatment options include medications, a type 2 diabetes diet, and other lifestyle changes.
Radiculopathy, a condition in which a nerve or nerves along the spine are compressed causing pain, numbness, weakenss, and tingling along the nerve(s). Some causes of radiculopathy include bone spurs, disc hernation, osteoarthritis, tumors, infection, and neuropathy. There are many types of radiculopathy, including cervical radiculopathy, lumbar radiculopathy, and thoracic radiculopathy. Treatment depends on the are of nerve compression. Surgery is generally not required.
Chronic pain is pain (an unpleasant sense of discomfort) that persists or progresses over a long period of time. In contrast to acute pain that arises suddenly in response to a specific injury and is usually treatable, chronic pain persists over time and is often resistant to medical treatments.
Diabetes and Foot Problems (Treatment)
Diabetes related foot problems can affect your health with two problems: diabetic neuropathy, where diabetes affects the nerves, and peripheral vascular disease, where diabetes affects the flow of blood. Common foot problems for people with diabetes include athlete's foot, fungal infection of nails, calluses, corns, blisters, bunions, dry skin, foot ulcers, hammertoes, ingrown toenails, and plantar warts.
Guillain-Barré Syndrome is an autoimmune disease of the nervous system due to damage to the myelin sheath around nerves. It is the most acquired nerve disease (neuropathy) and usually follows a virus infection but can also be associated with immunizations, surgery, and childbirth. The cause is unknown but appears to be related to autoimmune reaction. Symptoms include weakness beginning in the legs and progressing upward, lost reflexes, and in severe cases breathing can be affected. Patients can expect a slow but progressive recovery over several months maintaining vital functions and passively exercising the muscles. Plasmapheresis (removing toxic substances from the blood) has been shown to improve outcome and shorten the disease as well as intravenous immunoglobulin.
Osteomyelitis is an infection of the bone. Potential causes include injections around the bone, fractures that puncture the skin, recent surgeries, and bacterial infections that travel from other areas of the body, spreading through the blood to the bone. Symptoms include pain, fever, chills, stiffness, and nausea. Treatment involves antibiotics and pain medications. Surgery is sometimes necessary.
Optic neuritis is inflammation of the optic nerve, the structure that connects the eye to the brain. The precise cause of optic neuritis is unknown, but it is thought to be a type of autoimmune disorder. Optic neuritis most commonly develops due to an autoimmune disorder that may be triggered by a viral infection.
Erectile Dysfunction (ED, Impotence)
Erectile dysfunction (ED, impotence) is the failure to achieve or maintain an erection. There are many potential underlying causes of erectile dysfunction, including stress and emotional problems, brain dysfunction, problems with blood supply to the penis, and structural problems with the penis. Erectile dysfunction is diagnosed by taking the patient's history and physical exam. Blood tests measuring kidney function and blood sugar, cholesterol, hormone, and prostate-specific antigen (PSA) levels may be ordered. Urinalysis, ultrasound, and other more sophisticated tests may be required. The treatment of erectile dysfunction depends on the underlying cause. Medications, penile injections, penile implants, and vacuum devices may be used. Treatment for erectile dysfunction is usually successful. The patient should manage heart disease risk factors (high blood pressure, high cholesterol, diabetes) as they are related to erectile dysfunction risk.
Neuropathic pain is a chronic condition that leads to ongoing pain symptoms. Patients can be predisposed to developing neuropathic pain who have conditions such as: diabetes, cancer, stroke, HIV, vitamin deficiencies, shingles, and multiple sclerosis. Patient history and nerve testing are used to diagnose neuropathic pain. Antidepressants, antiseizure medications, and other types of medications are used to treat neuropathic pain. Many people with neuropathic pain are able to attain some level of relief.
Diabetic Neuropathy (Symptoms, Causes, Diagnosis, Treatment)
Diabetic neuropathy a condition in which nerve damage has occurred as a complication of diabetes. The pain from the nerve damage can be severe with tingling or numbness in the part of the body affected. Diabetic neuropathy can occur anywhere in the body. Diabetic neuropathy can cause symptoms like intense pain, numbness, burning, or tingling in the part of the body affected by the condition. There are four types of neuropathy include peripheral, autonomic, proximal and focal. Natural therapies and medications may help relieve the pain and other symptoms of diabetic neuropathy.
Type 1 Diabetes (Symptoms, Causes, Diet, Treatment, Life Expectancy)
Type 1 diabetes mellitus (juvenile) is an auto-immune disease with no known cause at this time, although there are a few risk factors. Symptoms of type 1 diabetes include frequent urination, unintentional weight loss, dry and itchy skin, vision problems, wounds that heal slowly, and excessive thirst. Type 1 diabetes is diagnosed with blood tests. A healthy lifestyle and controlling blood glucose levels can improve life expectancy.
Sex, Urinary, and Bladder Problems of Diabetes
Having diabetes can mean early onset and increased severity of bladder symptoms (urinary incontinence and urinary tract infections) and changes in sexual function. Men may have erectile dysfunction; and women may have problems with sexual response and vaginal lubrication. Keep your diabetes under control, and you can lower your risk of sexual and urologic problems.
Eye Problems and Diabetes
Diabetes and eye problems are generally caused by high blood sugar levels over an extended period of time. Types of eye problems in a person with diabetes include glaucoma, cataracts, and retinopathy. Examples of symptoms include blurred vision, headaches, eye aches, pain, halos around lights, loss of vision, watering eyes. Treatment for eye problems in people with diabetes depend on the type of eye problem. Prevention of eye problems include reducing blood pressure, cholesterol levels, quitting smoking, and maintaining proper blood glucose levels.
Human Immunodeficiency Virus (HIV)
HIV (human immunodeficiency virus) infection left untreated causes AIDS (acquired immunodeficiency syndrome). Still incurable, AIDS describes immune system collapse that opens the way for opportunistic infections and cancers to kill the patient. Early symptoms and signs of HIV infection include flu-like symptoms and fungal infections, but some people may not show any symptoms for years. Highly active antiretroviral therapy (ART) is the standard treatment for HIV infection. These combination drug regimens have made HIV much less deadly, but a cure or vaccine for the pandemic remains out of reach. HIV is usually transmitted through sexual contact or sharing IV drug needles, but can also infect someone through contact with infected blood. Sexual abstinence, safe sex practices, quitting IV drugs (or at least using clean needles), and proper safety equipment by clinicians and first responders can drastically reduce transmission rates for HIV/AIDS.
Meralgia paresthetica is an entrapment or "pinching" of the nerve (lateral femoral cutaneous nerve) that supplies sensation to the outer portion of the thigh. Pressure on the nerve can result in burning, pain, and numbness on the outer or front part of the thigh. Treatment usually involves addressing the underlying cause but can also be treated by local cortisone injection and in rare cases surgical release of the nerve.
AIDS (Acquired Immunodeficiency Syndrome)
AIDS is the advanced stage of HIV infection. Symptoms and signs of AIDS include pneumonia due to Pneumocystis jiroveci, tuberculosis, toxoplasmosis, seizures, weakness, meningitis, yeast infection of the esophagus, and Kaposi's sarcoma. Anti-retroviral therapy (HAART) is used in the treatment of AIDS.
Diabetes and Kidney Disease
In the United States diabetes is the most common cause of kidney failure. High blood pressure and high levels of blood glucose increase the risk that a person with diabetes will eventually progress to kidney failure. Kidney disease in people with diabetes develops over the course of many years. albumin and eGFR are two key markers for kidney disease in people with diabetes. Controlling high blood pressure, blood pressure medications, a moderate protein diet, and compliant management of blood glucose can slow the progression of kidney disease. For those patients who's kidneys eventually fail, dialysis or kidney transplantation is the only option.
ALS (Amyotrophic Lateral Sclerosis) Symptoms, Causes, Life Expectancy
Amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease) is a neurological disease that progresses rapidly. The disease attacks the nerve cells responsible for the control of voluntary muscles. Early symptoms include cramping, twitching, or stiffness of the muscles; slurred nasal speech; difficulty swallowing or chewing, and muscle weakness in an arm or leg. Currently, the cause of ALS is not known. ALS is a fatal disease. No cure has been found for ALS, however, the drug riluzole (Rilutek) is FDA approved, and this drug reduces the damage to motor neurons by decreasing the release of glutamate.
Charcot-Marie-Tooth Disease (CMT)
Charcot-Marie-Tooth disease is one of the most common inherited neurological disorders. Charcot-Marie-Tooth disease affects the peripheral nerves. CMT symptoms and signs include weakness of the lower leg muscles and foot, foot drop, foot deformities, etc. There are several forms of Charcot-Marie-Tooth disease. Inherited gene mutations are the cause of Charcot-Marie-Tooth disease. There is no cure for Charcot-Marie-Tooth disease, however, therapeutic measures and mild exercise may help symptoms.
HIV vs. AIDS
Human immunodeficiency virus causes HIV infection. Acquired immunodeficiency syndrome (AIDS) is a condition that results after HIV has extensively damaged a person's immune system. Risk factors for HIV and AIDS include use of contaminated needles or syringes, unprotected sex, STDs, receiving a blood transfusion prior to 1985 in the United States, having many sex partners, and transmission from a mother to her child.
Pain Management: Neuropathic Pain
Neuropathic pain is chronic pain resulting from injury to the nervous system. The injury can be to the central nervous system (brain and spinal cord) or the peripheral nervous system (nerves outside the brain and spinal cord).
Nerve Disease and Bladder Control
A nerve problem might affect your bladder control if the nerves that are supposed to carry messages between the brain and the bladder do not work properly. Such problems include urine retention, poor control of sphincter muscles, and overactive bladder. Treatment depends upon the cause of the nerve damage and resulting type of bladder control problem.
Certain behavioral, lifestyle, and environmental factors contribute to cancer. Cancer prevention involves modifying these factors to decrease cancer risk. Tobacco use, alcohol consumption, physical inactivity, inadequate fruit and vegetable intake, and obesity increase the risk of certain cancers. Vaccines, genetic testing, and cancer screening also play a role in cancer prevention.
Lead-based paint and lead contaminated dust are the main sources of exposure for lead in U.S. children. Lead-based paints were banned for use in housing in 1978. All houses built before 1978 are likely to contain some lead-based paint. However, it is the deterioration of this paint that causes a problem. Approximately 24 million housing units have deteriorated leaded paint and elevated levels of lead-contaminated house dust. More than 4 million of these dwellings are homes to one or more young children. Lead poisoning is entirely preventable. The key is stopping children from coming into contact with lead and treating children who have been poisoned by lead.
Local ResourcesFind a local Neurologist in your town
Treatment & Diagnosis
- Tingling in Hands and Feet
- Toe Pain
- Numbness Toes
- Hand and Finger Numbness
- Finger Pain
- Hand Pain
- Arm Pain
- Leg Sores
- Foot Pain
- Excessive Sweating (Hyperhidrosis)
- Cold Hands
- Unsteady Gait
- Chronic Pain
- How to Choose a Doctor
- Doctor: Checklist to Take To Your Doctor's Appointment
- Doctor: Getting the Most from Your Doctor's Appointment
Medications & Supplements
- Antidepressants (Depression Medications)
- carbamazepine - oral, Tegretol
- alprazolam extended-release - oral, Xanax XR
- duloxetine - oral, Cymbalta
- gabapentin solution - oral, Neurontin
- clonazepam disintegrating tablet - oral
- diazepam - oral, Valium
- carbamazepine suspension - oral, Tegretol
- clonazepam - oral, Klonopin
- dextroamphetamine/amphetamine- oral, Adderall
- alprazolam concentrate solution - oral, Alprazolam Intensol
- carbamazepine chewable tablet - oral, Tegretol
- brimonidine solution - ophthalmic, Alphagan P
- baclofen - oral, Lioresal
- alprazolam - oral, Xanax
- carbamazepine extended-release - oral, Carbatrol, Tegretol XR
- zolpidem - oral, Ambien
- gabapentin - oral, Neurontin
- metronidazole (Flagyl, Flagyl ER) Antibiotic
- CARBAMAZEPINE EXTENDED RELEASE TABLETS-ORAL, Tegretol XR
- aspirin (acetylsalicylic acid, Bayer, Ecotrin, and others)
- acetaminophen (Tylenol, Tylenol Arthritis Pain, Tylenol Ext, Little Fevers Children's Fever/Pain)
- Lyrica (pregabalin)
- ibuprofen (Advil, Motrin, Nuprin)
- Cymbalta (duloxetine)
- Over-the-Counter Products
- Cymbalta vs. Wellbutrin Comparison
- cyanocobalamin (Vitamin B-12)
- Lyrica (pregabalin) vs. Cymbalta (duloxetine)
- amitriptyline (Elavil, Endep)
- Celexa vs. Cymbalta (Comparison of Differences and Similarities)
- chlordiazepoxide (Librium)
- magnesium supplement - oral, Uro-Mag
- nortriptyline (Pamelor)
- oxazepam (Serax, Zaxopam)
- clorazepate - oral, Tranxene
- iron/vitamin c/vitamin b12/intrinsic factor - oral, Foltrin
- calcium supplement/vitamin d - oral, Citracal + D, Os-Cal, Oyster S
- carbamazepine, Tegretol, Tegretol XR , Equetro, Carbatrol, Epitol, Teril
- cyanocobalamine (Vitamin B12)
- desipramine (Norpramin)
- thiamine - oral, Thiamilate
- vincristine - injection, Oncovin
- dextroamphetamine sustained-action capsule - oral, Dexedrine
- dantrolene - oral, Dantrium
- loxapine - oral, Loxitane
- dextroamphetamine (Dexedrine, Dextrostat, ProCentra, Zenzedi)
- pyridoxine - oral, Neuro-K, Vitamin B-6
- capsaicin - topical, Capsagel, Salonpas-Hot, Zostri
- potassium supplement effervescent tablet- oral
- Cyanokit (hydroxocobalamin injection)
Prevention & Wellness
- FDA Grants First Approvals for Generic Versions of Lyrica
- Health Tip: Symptoms of Neuropathy Caused By Chemo
- Blame Diabetes: Rates of 2 Nerve Conditions on the Rise
- Brain Training for Cancer Survivors' Nerve Damage
- FDA Bolsters Warnings About Class of Antibiotics
- Health Tip: If You Have Peripheral Neuropathy
- Diabetes-Related Foot Condition Often Missed
- Some Antibiotics Linked to Serious Nerve Damage
- Antidepressant Lessens Chemo-Related Pain
- Health Tip: Diabetes Often Triggers Foot Problems
- Sleep Apnea May Be Linked to Nerve Damage in Diabetics
- Antidepressant Cymbalta Might Ease Chemo-Linked Pain
- Many Primary Care Docs Don't Know Long-Term Effects of Chemo: Survey
- Many Docs Use Costly MRIs to Diagnose Nerve Condition: Study
- Driving Isn't An Issue for Most People With Diabetes
- Acupuncture Might Ease Chemotherapy Pain
- Nerve Damage May Play a Role in ED
- Genetic Clue to Painful Peripheral Neuropathy
- Breast Cancer Drug Eribulin Extends Survival