Periodic Paralysis Syndrome (Types, Symptoms, Diagnosis, and Diet) Center

Periodic paralysis syndrome comprises several types of rare muscle diseases in which a person experiences temporary muscle paralysis of one area of the body, or the entire body for a few minutes or days. The person regains normal muscle strength between periods of muscle weakness. You inherit the syndrome from your biological mother or father, or from a mutation in your genes. This gene mutation determines the type of periodic paralysis you have. The other symptoms depend upon the type of periodic paralysis you have.

For example:

  1. Hyperkalemic periodic paralysis is usually seen in children under the age of 10. An early symptom may be a lagging eyelid.
  2. Normokalemic periodic paralysis causes weakness.
  3. Hypokalemia periodic paralysis 1 or hypoPP1L usually begins in childhood with symptoms of episodic muscle weakness in addition to irregular heartbeats. The symptoms may last through age 20-40.
  4. Hypokalemia periodic paralysis 2 or hypoPP2 has the same signs and symptoms as hypoPP1.
  5. Thyrotoxic periodic paralysis or TPP causes symptoms of weakness that involves the muscles that help you breathe.
  6. Paramyotonia Congenita or PCM produces symptoms like a weakness response to cold or increased activity and muscle weakness and rigidity.
  7. Potassium aggravated myotonias, when triggered by exercise can an attack of muscle stiffness.
  8. Andersen-Tawil syndrome or ATS cause symptoms of irregular heart rhythms.
  9. Familial periodic paralysis is a term used by doctors to describe four of the periodic paralysis syndromes.

Treatment of periodic paralysis syndrome depends upon the kind of syndrome you have. Your doctor may make changes to your diet and prescribe prescription medication.

REFERENCE: Stripathi, N., MD. "Periodic paralyses." Medscape. Updated: May 18, 2017.
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