Medical Definition of PEP

Reviewed on 6/3/2021

PEP: The abbreviation PEP stands for a number of things in medicine including post-exposure prophylaxis. Prophylaxis means a defense or protection.

Post-exposure prophylaxis, for example, might concern the treatment of a health care worker exposed by a needle stick to HIV with a drug such as AZT to protect them from being infected with HIV.

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