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- What is penicillin v potassium? What is penicillin v potassium?
- What are the side effects of penicillin v potassium?
- What is the dosage for penicillin v potassium?
- Which drugs or supplements interact with penicillin v potassium?
- Is penicillin v potassium safe to take if I'm pregnant or breastfeeding?
- What else should I know about penicillin v potassium?
What is penicillin v potassium? What is penicillin v potassium?
Penicillin V potassium is penicillin antibiotic that is administered orally. Penicillin V potassium kills bacteria by inhibiting bacterial cell wall synthesis. Some bacterial species against which penicillin V potassium has shown high in-vitro activity include some species of staphylococci, streptococci (groups A, C, G, H, L, and M), and pneumococci. Other bacterial species against which this medication has activity includes Corynebacterium diphtheria, Bacillus anthracis, Clostridia, Actinomyces bovis, Streptobacillus moniliformis, Listeria monocytogenes, Leptospira, Neisseria gonorrhea, and Treponema pallidum.
Penicillin V potassium offers some distinct advantages over penicillin G. Penicillin V potassium is much more resistant to inactivation by stomach acidity, and therefore results in better drug absorption and higher levels in the blood. On average, blood levels of penicillin V potassium is two to five times higher than that observed with same dose of oral penicillin G.
Penicillin V potassium was approved by the US Food and Drug Administration (FDA) in 1956.
What brand names are available for penicillin v potassium?
Beepen-VK, Penicillin VK, V-Cillin-K
Is penicillin v potassium available as a generic drug?
Do I need a prescription for penicillin v potassium?
What are the side effects of penicillin v potassium?
The most common side effects to oral penicillin are:
Rare (occurring at frequency of <1%) but serious side effects include:
Hypersensitivity reactions have been reported with penicillin use.
What is the dosage for penicillin v potassium?
The usual recommended dosage for adults and children 12 years and older are as follows:
Which drugs or supplements interact with penicillin v potassium?
Penicillin V potassium may inhibit the renal tubular secretion (elimination of the drug via the kidneys) of methotrexate (Trexall, Rheumatrex). Co-administration may result in higher blood levels of methotrexate and increases the risk of methotrexate toxicity (side effects).
Penicillin V potassium may interfere with the effectiveness of the live typhoid vaccine. Administration of the vaccine must be separated by at least 24 hours from the last dose of the antibiotic.
Antibiotics such as penicillin V potassium may decrease the effectiveness of certain oral contraceptives or birth control pills. Patients may use an alternative form of birth control (for example, condoms) while on antibiotic therapy to prevent unexpected pregnancies.
Penicillin antibiotics may inhibit vitamin K synthesis due to their effect on the normal intestinal flora. Therefore, co-administration of warfarin (a vitamin K antagonist) with penicillin V potassium may increase the risk of bleeding.
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Is penicillin v potassium safe to take if I'm pregnant or breastfeeding?
Penicillin V potassium is classified as FDA pregnancy risk category B (Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women). Use of penicillin products in humans has not shown any evidence of fetal harm. Additionally, no evidence of fetal harm has been reported in animal studies. However, there is a lack of adequate and well controlled studies in pregnant women. As with all medications, use of penicillin V potassium during pregnancy requires careful evaluation of treatment benefits and potential risk to the fetus.
Penicillin V potassium is excreted in breast milk. Penicillin products have been reported to cause diarrhea, candidiasis (fungal infections), and skin rash in breast feed babies. Due to the lack of safety data, this medication should be used cautiously in females who are breastfeeding. Penicillin type antibiotics are used for treating infection in children.
What else should I know about penicillin v potassium?
What preparations of penicillin v potassium are available?
Powder for oral solution: 125 mg/5 ml (100 ml, 200 ml); 250 mg/5 ml (100 ml, 200 ml); Tablets: 250 mg, 500 mg
How should I keep penicillin v potassium stored?
Reconstituted product may be stored for up to 14 days and requires refrigeration 2.2 C to 7.7 C (36 F to 46 F). Un-reconstituted product and oral tablets may be stored at room temperature between 20 C to 25 C (68 F to 77 F).
Penicillin V potassium (Beepen-VK, Penicillin VK, V-Cillin-K) is an antibiotic prescribed to treat a variety of infections such as the respiratory tract, middle ear, skin, sinuses, and soft tissues. Penicillin V potassium also is prescribed to prevent rheumatic fever. Side effects, drug interactions, patient safety, storage, and dosage information should be reviewed prior to taking this medication.
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Sinus infection (sinusitis) is caused by allergies, infection, and chemicals or other irritants of sinuses. Signs and symptoms include headache, fever, and facial tenderness, pressure, or pain. Treatments of sinus infections are generally with antibiotics and at times, home remedies.
Cellulitis is an acute spreading bacterial infection below the surface of the skin characterized by redness, warmth, inflammation, and pain. The most common cause of cellulitis is the bacteria staph (Staphylococcus aureus).
Upper Respiratory Infection (URI)
An upper respiratory infection is a contagious infection of the structures of the upper respiratory tract, which includes the sinuses, nasal passages, pharynx, and larynx. Common causes of an upper respiratory infection include bacteria and viruses such as rhinoviruses, group A streptococci, influenza, respiratory syncytial, whooping cough, diphtheria, and Epstein-Barr. Examples of symptoms of upper respiratory infection include sneezing, sore throat, cough, fever, and nasal congestion. Treatment of upper respiratory infections are based upon the cause. Generally, viral infections are treated symptomatically with over-the-counter (OTC) medication and home remedies.
Middle Ear Infection (Otitis Media)
A middle ear infection (otitis media) can cause earache, temporary hearing loss, and pus drainage from the ear. It is most common in babies, toddlers, and young children. Learn about causes and treatment.
Pneumonia is inflammation of the lungs caused by fungi, bacteria, or viruses. Symptoms and signs include cough, fever, shortness of breath, and chills. Antibiotics treat pneumonia, and the choice of the antibiotic depends upon the cause of the infection.
Strep throat is a bacterial infection of the throat. Signs and symptoms of strep throat include headache, nausea, vomiting, sore throat, and fever. Strep throat symptoms in infants and children are different than in adults. Strep throat is contagious and is generally passed from person to person. Treatment for strep throat symptoms includes home remedies and OTC medication; however, the only cure for strep throat are antibiotics.
Group A Streptococcal Infections
Second Source article from Government
Rheumatic fever is a disease that sometimes occurs after a group A streptococcal infection of the throat. Symptoms and signs include carditis, polyarthritis, Aschoff bodies, rash, Sydenham's chorea, and fever. Treatment for rheumatic fever involves eliminating the bacteria with penicillin, erythromycin, or azithromycin. Further treatment focuses on alleviating the symptoms brought on by the body's immunologic response to the bacteria.
Group A streptococcal infections are caused by group A Streptococcus, a bacteria that causes a variety of health problems, including strep throat, impetigo, cellulitis, erysipelas, and scarlet fever. There are more than 10 million group A strep infections each year.
Vancomycin-Resistant Enterococci (VRE)
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Clostridium Difficile Colitis (C. diff, C. difficle Colitis)
Clostridium difficile (C. difficile) is a bacterium, and is one of the most common causes of infection of the colon. C. difficile spores are found frequently in hospitals, nursing homes, extended care facilities, and nurseries for newborn infants.
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Antibiotic Resistance (Drug Resistance, Antimicrobial Resistance)
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