PANDAS: Symptoms & Signs

Medically Reviewed on 9/2/2020

PANDAS is a term that refers to a rare condition known as pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections. PANDAS leads to behavioral changes in children following a streptococcal infection and was first described in the 1990s. It is believed the behavioral symptoms come from an immune system attack on the individual's own brain cells.

Signs and symptoms of PANDAS can include

Other associated symptoms and signs can include

Those affected may also develop symptoms characteristic of attention deficit hyperactivity disorder (ADHD).

Cause of PANDAS

Doctors believe an autoimmune reaction to a group A streptococcal bacterial infection (such as strep throat, scarlet fever, cellulitis, or others) causes PANDAS.

Other pandas symptoms and signs


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Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.