- Determining Prognosis
- Survival Rate Chart
- Treatment Options
People can live without a fully functional pancreas but not without a liver. Liver failure resulting from metastasis from these tumors is the most common cause of death in patients affected by the tumor.
How do doctors determine the prognosis of pancreatic neuroendocrine tumors?
After the diagnosis of a pancreatic neuroendocrine tumor has been confirmed, the doctor must determine the stage and grade of cancer. This helps them decide the course of treatment and estimate the chances of survival.
Staging of cancer
Grading the cancer
Grading lets the doctor know how different the cancer cells look from normal cells. This provides an idea about the speed of growth and spread of cancer. The tumor will be given a grade between I and III. A lower number indicates slow-growing cancer.
What is the life expectancy of someone with pancreatic neuroendocrine cancer?
The lifespan of a patient with a pancreatic neuroendocrine tumor depends on the stage and grade of their cancer. Studies that have observed patients with pancreatic neuroendocrine tumors for five years and more provide an estimate of the number of people living with the tumor for at least five years. This is known as a five-year survival rate.
|Stage of tumor||5-year survival rate (in percentage)|
Localized tumor: This refers to the tumor that has not spread to other parts of the body from where it started. The five-year survival rate for people with localized pancreatic neuroendocrine tumors is 93 percent, which means 93 percent of patients can expect to live for five years or more.
Regional tumor: This refers to the tumor that has spread to nearby tissue or the regional lymph nodes. The five-year survival rate for regional pancreatic neuroendocrine tumors is 77 percent.
Metastatic tumor: If the tumor has spread to distant areas of the body, such as the liver, the survival rate is 25 percent.
How is pancreatic neuroendocrine tumor treated?
To decide the best treatment, the doctor will first assess the following factors:
- The stage and grade of the cancer
- Age of the patient
- Other health problems that the patient has
- The patient’s preferences
Treatments are available for all stages of cancer. Even the advanced stage of cancer will benefit from treatments to relieve symptoms.
The types of treatments to treat pancreatic neuroendocrine cancer include:
Surgery is preferred if the pancreatic neuroendocrine tumor is restricted only to the pancreas. The surgery will involve removing a part or most of the pancreas. If cancer has spread beyond the pancreas, surgery may not help and other treatments may be preferred.
Tumor ablation and embolization
Tumor ablation or embolization is done if a pancreatic neuroendocrine tumor has spread to the liver. It destroys the tumor and may be done in any of the following ways:
- Killing the tumor cells with radio waves or microwaves
- Freezing and destroying the tumor cells (cryoablation)
- Blocking the blood supply to the tumor
Chemotherapy involves using drugs that kill the cancer cells. Given in either the form of pills or injections, these drugs are taken in multiple sessions lasting months or years with intervals in between.
This therapy uses strong radiation that targets the tumor and shrinks it. It may be given after surgery to destroy the remaining part of the tumor.
Latest Cancer News
Daily Health News
Health Solutions From Our Sponsors
American Cancer Society. Survival Rates for Pancreatic Neuroendocrine Tumor. https://www.cancer.org/cancer/pancreatic-neuroendocrine-tumor/detection-diagnosis-staging/survival-rates.html
Top Pancreatic Neuroendocrine Tumors Metastasize Related Articles
Cancer 101 SlideshowLearn the basics about cancer including types, causes, how it spreads, symptoms and signs, stages and treatment options. Read about the common type of cancers.
Do Blood Tests Show Pancreatic Cancer?Blood tests are often used in combination with other clinical assessments and tests to diagnose pancreatic cancer.
What Are the Early Warning Signs of Pancreatic Cancer?Pancreatic cancer does not show its signs and symptoms in its early stages. Only when it has grown large enough, it begins to exhibit its warning signs and symptoms. Symptoms of pancreatic cancer include jaundice (yellowing of the eyes and skin), belly or back pain, unintended weight loss, poor appetite, nausea and vomiting, enlarged gallbladder or liver, deep vein thrombosis or DVT (blood clots in a large vein, usually in the leg), and diabetes.
How Is Pancreatic Neuroendocrine Tumor Diagnosed?Here are the eight diagnostic tests doctors may use to diagnose pancreatic neuroendocrine tumors.
Is Chemo Worth It for Pancreatic Cancer?Chemotherapy is usually the main treatment for pancreatic cancer since it can sometimes shrink or slow the growth of cancer, prolonging one’s lifespan.
Is Pancreatic Cancer the Most Painful?Pancreatic cancer is one of the most painful types of cancer because it invades and presses on the nerves near the pancreas leading to pain in the back or abdomen. Pain seems to be the most distressing symptom in patients with pancreatic cancer.
Pancreatic CancerPancreatic cancer is a malignant tumor of the pancreas. Pancreatic cancer has been called a "silent" disease because early pancreatic cancer usually does not cause early symptoms. Typically, pancreatic cancer has metastasized (spread to adjacent organs, such as the liver) by the time most people receive a dignosis of pancreatic cancer. Symptoms and signs usually appear later in the course of the disease and include jaundice, back pain, nausea, weight loss, itching, and loss of appetite. Treatment depends upon the type of pancreatic cancer but may include surgery, chemotherapy, and/or radiation therapy.
Can Pancreatic Cancer Be Detected by Blood Test?Currently, there is no blood test to confirm the diagnosis of pancreatic cancer. A doctor may suggest doing a blood tumor markers test for pancreatic cancer along with routine blood tests and radiological tests to confirm the diagnosis.
Pancreatic Cancer PictureAn abdominal CT scan shows a small, vaguely seen 2-cm pancreatic adenocarcinoma (mass) causing obstruction of both the common bile duct (cbd) and pancreatic duct (pd). See a picture of Pancreatic Cancer and learn more about the health topic.
Pancreatic Neuroendocrine Tumors (Islet Cell Tumors)There are many types of pancreatic neuroendocrine tumors (NETs): gastrinoma, insulinoma, glucagonoma, VIPomas, and somatostatinomas. Symptoms and signs vary with the type of pancreatic NET. Standard treatments include surgery, chemotherapy, hormone therapy, chemoembolization, targeted therapy, and supportive care.
Targeted Therapy: What Are Invasion and Metastasis in cancer?There are several proteins and cellular signals that cancerous or malignant tumor cells employ for promoting invasion and metastasis. Targeted cancer therapies are in development to chemically hinder invasion and metastasis. Targeted therapy, in general, by identifying and targeting cancer-causing factors. Targeted therapy medications do not directly kill the cancer cells, but work on the cellular level to stop their growth and prevent cancer from spreading to other parts of the body.
What Does Pancreatic Cancer Back Pain Feel Like?Pancreatic cancer is hard to be recognized in its earlier stages as its signs and symptoms may resemble vague gastrointestinal complaints. Pain in the abdomen or back is its common symptom. It is mostly intermittent initially, that is, it comes and goes. But with time, it becomes more frequent.
What Is the Most Common Site of Metastasis?Cancer can spread to almost any part of the body, although different cancers are likely to metastasize to certain areas than others. The most common site of metastasis for different primary cancer is tabulated
What Is the #1 Cause of Pancreatic Cancer?Pancreatic cancer occurs when cells begin to grow uncontrollably and form tumors within the pancreas. The exact cause of pancreatic cancer is unknown. However, doctors have identified some risk factors that increase your chances of developing pancreatic cancer. These include being over 45 years old, male gender, African American race, cigarette smoking, alcohol abuse, regular consumption of high dietary fats, obesity, type 2 diabetes, chronic pancreatitis, family history of pancreatic cancer, and heavy exposure to certain chemicals used in the dry cleaning and metalworking industries.