Paget's Disease of Bone: Symptoms & Signs

Paget's disease of bone (which is different from Paget's disease of the breast) is a chronic disease of bone characterized by excessive breakdown and reformation of bone. This process leads to abnormal enlargement and bone deformities.

Paget's disease of bone may not produce symptoms. If symptoms and signs are present, these can include bone pain in the affected area. The spine, the thighbone (femur), the pelvis, the skull, collarbone (clavicle), and the upper arm bone (humerus) are the most common sites of involvement. Other signs and associated symptoms can include bowed legs, abnormalities with walking, and sensations of tingling (pins and needles feeling) and numbness. Bone fractures may also occur.

Cause of Paget's disease of bone

Medical professionals do not understand the cause of Paget's disease of bone.

Other paget's disease of bone symptoms and signs

  • Bone Pain
  • Bowed Legs
  • Fractures
  • Tingling Sensation
  • Walking Abnormalities

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Medically Reviewed on 9/10/2019
References
Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.