Medical Definition of Paget-Schroetter Syndrome

Reviewed on 5/3/2022

Paget-Schroetter syndrome is a condition characterized by blood clotting (thrombosis) in the axillary and subclavian veins of the chest that is caused by repeated and vigorous activity such as over-the-head motion of their arms. The condition is most common in people in their 20s and 30s and is more common in men than in women. Sports activities that involve overhead motion of the arms include baseball or softball pitching, swimming, rowing, or weightlifting. Signs and symptoms include

  • painful arms,
  • upper arm swelling,
  • bluish discoloration of the skin in the affected area, and
  • enlargement of the affected arm.

The symptoms may come on suddenly or may develop over time.



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Saleem, Taimur, and Donald T. Baril. "Paget Schroetter Syndrome." [Updated 2022 Jan 11]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: <>.