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- Take the Pain Quiz
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Oxycodone vs. codeine
- Oxycodone (OxyContin, Roxicodone, Oxecta, Oxaydo, Xtampza ER, and Roxybond) and codeine are both narcotic pain relievers. Both are also used as cough suppressants similar to morphine and hydrocodone.
- Oxycodone and codeine also cause sedation and drowsiness, and depress breathing.
- Both drugs are available in generic form.
- Both oxycodone and codeine are often available in forms combined with other non-narcotic pain relievers such as acetaminophen (Tylenol) or aspirin.
- Similar side effects of oxycodone and codeine include lightheadedness, dizziness, sedation, nausea, vomiting, constipation, dry mouth, itching, and rash.
- Combining opioids such as oxycodone and codeine with alcohol or other central nervous system depressants may result in severe sedation, respiratory depression, coma, and death.
- Both oxycodone and codeine have potential for abuse and addiction. Withdrawal symptoms for both drugs include restlessness, watery eyes, runny nose, yawning, sweating, chills, muscle pain, and dilated pupils.
What is oxycodone? What is codeine? How do they work?
Codeine is another narcotic pain-reliever and cough suppressant similar to morphine and hydrocodone. The mechanism of action of codeine is not known but codeine binds to receptors in the brain and increases tolerance to pain, decreasing discomfort, but the pain still is apparent to the patient. Codeine also causes sedation and drowsiness, and depresses breathing. Codeine is often combined with acetaminophen or aspirin for more effective pain relief.
What are the uses for oxycodone vs. codeine?
Oxycodone is prescribed for the management of pain severe enough to require daily, around-the-clock, long-term treatment with a narcotic, and for which alternative treatment options are inadequate for the relief of moderate to severe pain.
Codeine is used for the relief of mild to moderately severe pain and for suppressing cough.
What are the side effects of oxycodone vs. codeine?
Codeine side effects
The most frequent side effects of codeine include:
- Shortness of breath
- Allergic reactions
- Abdominal pain
Serious side effects of codeine include:
- Life-threatening respiratory depression
- Severe low blood pressure
- Adrenal insufficiency
- Accidental ingestion of codeine can result in fatal overdose
Oxycodone side effects
The most frequent side effects of oxycodone include:
- Dry mouth
- Urinary retention
Other side effects of oxycodone include:
- Heart attack
- Abnormal heartbeats
Oxycodone can depress breathing and is used with caution in elderly, debilitated patients and in patients with serious lung disease.
Oxycodone can impair thinking and the physical abilities required for driving or operating machinery.
Oxycodone is habit forming. Mental and physical dependence can occur but are unlikely when used for short-term pain relief. If oxycodone is suddenly withdrawn after prolonged use, symptoms of withdrawal may develop. The dose of oxycodone should be gradually reduced in order to avoid withdrawal symptoms.
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What is the dosage for oxycodone vs. codeine?
- The usual starting dose using immediate release oxycodone tablets is 5 to 30 mg every 4 to 6 hours. Patients who have never received opioids should start with 5-15 mg every 4 to 6 hours. Some patients may require 30 mg or more every 4 hours.
- The usual starting dose using extended release tablets is 10 mg every 12 hours. Extended release tablets are used when around the clock treatment is required for an extended period. Extended release tablets should not be broken, crushed, or chewed but should be swallowed whole. Breaking, crushing or chewing extended release tablets may lead to rapid absorption of the drug and dangerous levels of oxycodone.
- Patients who have been using opioids and have become tolerant to opioid therapy should only use the 60 and 80 tablets or single doses greater than 40 mg. Administration of large doses to opioid-naïve patients may lead to profound depressed breathing. Administration of large doses to opioid-naïve patients may lead to profound depression of breathing.
- The usual adult dose of the oral concentrate (20 mg/ml) is 5 mg every 6 hours.
- The usual adult dose for the oral solution (5 mg/5 ml) is 10-30 mg every 4 hours.
- The usual adult dose of codeine for pain is 15-60 mg every 4-6 hours as needed.
- The dose for cough is 10 to 20 mg every 4-6 hours as needed.
- The maximum dose for treating cough is 120 mg every 24 hours.
Are oxycodone or codeine safe to take if I am pregnant or breastfeeding?
- Safety during pregnancy has not been established. Children born to mothers who were taking oxycodone for a prolonged period may exhibit respiratory depression or withdrawal symptoms.
- Small amounts of oxycodone are secreted in breast milk, which may cause side effects in the newborn.
- Small amounts of codeine are secreted in breast milk, but the risk of adverse events in the infant is small.
Codeine and oxycodone are both opioid (narcotic) pain relievers and cough suppressants. Codeine and oxycodone both are similar to hydrocodone and morphine. Similar side effects of oxycodone and codeine include constipation, dry mouth, itching, rash, dizziness, sedation, and lightheadedness. Serious side effects of codeine include severe low blood pressure (hypotension), adrenal insufficiency, and life-threatening respiratory depression. Serious side effects of oxycodone include heart attack, depression, and abnormal heartbeats.
Both codeine and oxycodone are addictive when taken long-term, and may cause withdrawal symptoms if stopped suddenly. Oxycodone or codeine taken accidentally can result in a fatal overdose.
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Related Disease Conditions
Testicular pain, or pain in the testicle or testicles are caused by a variety of diseases or conditions such as testicular trauma, testicular torsion, varicoceles, testicular cancer, epididymitis caused by infections such as STDs, and orchitis. Common symptoms of pain in the testicle or testicles are abdominal pain, urinary pain or incontinence, fever, nausea, vomiting, and pain in the scrotum or testicle. Treatment depends on the cause of the testicular pain or pain in the testicles.
Lower Back Pain
There are many causes of back pain. Pain in the low back can relate to the bony lumbar spine, discs between the vertebrae, ligaments around the spine and discs, spinal cord and nerves, muscles of the low back, internal organs of the pelvis and abdomen, and the skin covering the lumbar area.
Coccydynia (Tailbone Pain)
Coccydynia is an inflammation of the bony area (tailbone or coccyx) located between the buttocks. Coccydynia is associated with pain and tenderness at the tip of the tailbone between the buttocks. Pain is often worsened by sitting. There are many causes of tailbone pain that can mimic coccydynia including: fracture, pilonidal cysts, infection, and sciatica. Treatment methods include medication and rest.
Cancer is a disease caused by an abnormal growth of cells, also called malignancy. It is a group of 100 different diseases, and is not contagious. Cancer can be treated through chemotherapy, a treatment of drugs that destroy cancer cells.
An abscessed tooth is an infection within a tooth that has spread to the root. Symptoms of an abscessed tooth may include pain, swelling, tenderness, redness, and the presence of a pus-filled lesion on the gum. A dental professional diagnoses an abscessed tooth and dental X-rays may be required. An abscessed tooth is treated with a root canal.
Shoulder and Neck Pain
Shoulder and neck pain may be caused by bursitis, a pinched nerve, whiplash, tendinitis, a herniated disc, or a rotator cuff injury. Symptoms also include weakness, numbness, coolness, color changes, swelling, and deformity. Treatment at home may incorporate resting, icing, and elevating the injury. A doctor may prescribe pain medications and immobilize the injury.
Foot pain may be caused by injuries (sprains, strains, bruises, and fractures), diseases (diabetes, Hansen disease, and gout), viruses, fungi, and bacteria (plantar warts and athlete's foot), or even ingrown toenails. Pain and tenderness may be accompanied by joint looseness, swelling, weakness, discoloration, and loss of function. Minor foot pain can usually be treated with rest, ice, compression, and elevation and OTC medications such as acetaminophen and ibuprofen. Severe pain should be treated by a medical professional.
A toothache is pain on or around a tooth. It may have a variety of causes, including a cavity, abscess, or even sinusitis. Toothache symptoms include pain, headache, earache, bad taste in the mouth, and gum swelling. Dental X-rays and other tests performed by a dentist are used to diagnose the cause of a toothache. Toothache treatment depends on the underlying cause. Taking proper care of the teeth and gums can help prevent toothache.
Neck Pain (Cervical Pain)
Neck pain (cervical pain) may be caused by any number of disorders and diseases. Tenderness is another symptom of neck pain. Though treatment for neck pain really depends upon the cause, treatment typically may involve heat/ice application, traction, physical therapy, cortisone injection, topical anesthetic creams, and muscle relaxants.
Ankle Pain (Tendinitis)
Ankle pain is commonly due to a sprain or tendinitis. The severity of ankle sprains ranges from mild (which can resolve within 24 hours) to severe (which can require surgical repair). Tendinitis of the ankle can be caused by trauma or inflammation.
Sacroiliac Joint Dysfunction (SI Joint Pain)
Sacroiliac joint (SI) dysfunction is a general term to reflect pain in the SI joints. Causes of SI joint pain include osteoarthritis, abnormal walking pattern, and disorders that can cause SI joint inflammation including gout, rheumatoid arthritis, psoriasis, and ankylosing spondylitis. Treatment includes oral medications, cortisone injections, and surgery.
Acute injuries, medical conditions, and chronic use conditions are causes of knee pain. Symptoms and signs that accompany knee pain include redness, swelling, difficulty walking, and locking of the knee. To diagnose knee pain, a physician will perform a physical exam and also may order X-rays, arthrocentesis, blood tests, or a CT scan or MRI. Treatment of knee pain depends upon the cause of the pain.
Wisdom teeth are the third set of molars that people get in their late teens or early twenties. Impacted wisdom teeth that only partially erupt allows for an opening for bacteria to enter around the tooth and cause an infection, which results in pain, swelling, jaw stiffness, and general illness. Before your wisdom teeth are pulled, the teeth and the surrounding tissue will be numbed with a local anesthetic. Recovery from wisdom tooth removal depends upon the difficulty of the extraction.
Elbow pain is most often the result of tendinitis, which can affect the inner or outer elbow. Treatment includes ice, rest, and medication for inflammation. Inflammation, redness, warmth, swelling, tenderness, and decreased range of motion are other symptoms associated with elbow pain. Treatment for elbow pain depends upon the nature of the patient's underlying disease or condition.
Arthritis, bursitis, IT band syndrome, fracture, and strain are just some of the causes of hip pain. Associated symptoms and signs include swelling, tenderness, difficulty sleeping on the hip, and loss of range of motion of the hip. Treatment depends upon the cause of the hip pain but may include anti-inflammatory medications and icing and resting the hip joint.
Pain management and treatment can be simple or complex, according to its cause. There are two basic types of pain, nociceptive pain and neuropathic pain. Some causes of neuropathic pain include: complex regional pain syndrome, interstitial cystitis, and irritable bowel syndrome. There are a variety of methods to treat chronic pain, which are dependant on the type of pain experienced.
Chronic pain is pain (an unpleasant sense of discomfort) that persists or progresses over a long period of time. In contrast to acute pain that arises suddenly in response to a specific injury and is usually treatable, chronic pain persists over time and is often resistant to medical treatments.
Dental injuries range from a chipped or fractured tooth to a knocked out tooth. Treatment depends upon the severity of the dental injury. Dental injuries may be prevented by aligning protruding front teeth with braces and using face masks and mouthguards while playing sports.
Myofascial Pain Syndrome
Myofascial pain syndrome is muscle pain in the body's soft tissues due to injury or strain. Symptoms include muscle pain with tender points and fatigue. Treatment usually involves physical therapy, massage therapy, or trigger point injection.
Pain Management: Musculoskeletal Pain
Natural menopause is the permanent ending of menstruation that is not brought on by any type of medical treatment. For women undergoing natural menopause, the process is described in three stages: perimenopause, menopause, and postmenopause. However, not all women undergo natural menopause. Some women experience induced menopause as a result of surgery or medical treatments, such as chemotherapy and pelvic radiation therapy.
Treatment & Diagnosis
- Muscle Pain (Myalgia)
- Chronic Pain
- Chronic Pain: Implantable Pain Control Devices
- Pain Management: Dealing with Back Pain
- Pain Management
- Pain Management: Painkiller Addiction
- Chronic Pain Treatments for Mind and Body
- Pain Awareness and Management
- Chronic Pain: Dealing With Back and Neck Pain
- Chronic Pain and Fatigue - What You Can Do
- Pain Management: Routes to Relief
Medications & Supplements
- Tramadol vs. Codeine
- tramadol (Ultram)
- codeine (for Pain)
- tramadol/acetaminophen - oral, Ultracet
- Benzodiazepines vs. Narcotics (Opioids)
- Oxycodone for Pain (OxyContin, Roxicodone, Oxecta, Oxaydo, Xtampza ER, Roxybond)
- Codeine vs. Vicodin
- Percocet (oxycodone and acetaminophen, Roxicet, Tylox, Oxycet)
- hydromorphone (Dilaudid)
- Cold Medicine and Cough Syrup for Adults
Prevention & Wellness
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