- Surprising Reasons You're in Pain Slideshow
- Take the Pain Quiz
- Joint-Friendly Exercises to Reduce RA Pain Slideshow
- What is Percocet (oxycodone and acetaminophen)?
- Is Percocet available as a generic drug?
- Do I need a prescription for Percocet?
- Why is Percocet prescribed to patients?
- What are the side effects of Percocet?
- Is Percocet addicting?
- What is the dosage for Percocet?
- Which drugs or supplements interact with Percocet?
- Is Percocet safe to use during pregnancy or while breastfeeding?
- What brand names are available for oxycodone and acetaminophen?
- What else should I know about Percocet?
What is Percocet (oxycodone and acetaminophen)?
Quick GuideChronic Pain Syndrome: Treatment and Management for CPS
Why is Percocet prescribed to patients?
- Percocet (oxycodone/acetaminophen) is prescribed for the relief of moderate to moderately-severe pain.
What are the side effects of Percocet?
The most frequent adverse reactions of Percocet (oxycodone/acetaminophen) include:
Other important side effects include:
- Spasm of the ureter, which can lead to difficulty in urinating
Possible serious side effects include:
- Severe reduction in blood pressure (hypotension)
- Paralytic ileus
- Serious allergic reactions
- Severe skin reactions
Oxycodone can depress breathing and, therefore, is used with caution in elderly, debilitated patients and in patients with serious lung disease. Oxycodone can impair thinking and the physical abilities required for driving or operating machinery.
Is Percocet addicting?
- Oxycodone can be habit-forming. Mental and physical dependence can occur, but are unlikely when used for short-term pain relief.
What is the dosage for Percocet?
- The dose of Percocet (oxycodone/acetaminophen) is variable and depends on the needs of the patient and specific circumstances.
- The usual dose is one tablet every six hours as needed.
- The maximum oxycodone/acetaminophen dose is 60 mg/4 g per day.
Which drugs or supplements interact with Percocet?
- Oxycodone, like other narcotic pain-relievers, increases the effect of drugs that slow brain function, such as alcohol, barbiturates, skeletal muscle relaxants, for example, carisoprodol (Soma), cyclobenzaprine (Flexeril), and benzodiazepines such as diazepam (Valium) and lorazepam (Ativan). A combined use of muscle relaxants or benzodiazepines and oxycodone may lead to increased respiratory depression.
- Since oxycodone causes constipation, the use of antidiarrheals, for example, diphenoxylate (Lomotil) and loperamide (Imodium), in persons taking oxycodone, can lead to severe constipation.
- Drugs which stimulate and also block opioid receptors, for example, pentazocine, nalbuphine (Nubain), butorphanol (Stadol), and buprenorphine (Subutex) may reduce the effect of oxycodone and may precipitate withdrawal symptoms.
- A fatty meal may increase the absorption of oxycodone by 27%.
Is Percocet safe to use during pregnancy or while breastfeeding?
- Safety of oxycodone/acetaminophen during pregnancy has not been established. Newborns of mothers who were taking oxycodone for a prolonged period may exhibit respiratory depression or withdrawal symptoms.
- Small amounts of oxycodone are secreted in breast milk and may cause side effects in the newborn.
What brand names are available for oxycodone and acetaminophen?
- Brand names available in the US include: Percocet, Primlev, Roxicet, Endocet, Xartemis XR
- Discontinued brand names include Xolox, Tylox, Oxycet, and Roxilox.
Daily Health News
What else should I know about Percocet?
What are preparations of Percocet available?
- Tablets: 2.5/325, 5/300, 5/325, 7.5/300, 7.5/325, 10/300, 10/325 mg (oxycodone/acetaminophen)
- Tablets (Extended Release): 4.8/325 mg.
- Solution: 5/325 mg per teaspoonful
How should I keep Percocet stored?
Oxycodone/acetaminophen should be stored at room temperature in a sealed, light-resistant container.
How does Percocet stop the pain?
- The precise mechanism of action of oxycodone is not known but may involve stimulation of opioid (narcotic) receptors in the brain. Oxycodone does not eliminate the sensation of pain but decreases discomfort by increasing tolerance to pain. In addition to tolerance to pain, oxycodone also causes sedation and respiratory depression. Acetaminophen is a non-narcotic pain reliever and antipyretic (fever reducer). Acetaminophen relieves pain by elevating the threshold to sensing pain. It reduces fever through its action on the heat-regulating center of the brain. The combination of oxycodone and acetaminophen achieves greater pain relief than either taken separately.
- The FDA approved oxycodone/acetaminophen combinations in February 1980.
Percocet (oxycodone and acetaminophen, Roxicet, Tylox, Oxycet) is a drug prescribed for the relief of moderate to moderately-severe pain. Common side effects may include:
Other brand names for oxycodone and acetaminophen are Roxicet, Tylox, Oxycet, Roxilox.
Multimedia: Slideshows, Images & Quizzes
Addicted to Pills: The Health Risks of Drug Abuse
What is drug abuse? Learn about prescription drug abuse and over-the-counter (OTC) drugs, including depressants, pain relievers,...
Prescription Drug Abuse: Know The Warning Signs
Learn about prescription drug abuse facts and statistics about the dangers and misconceptions of abusing common prescription...
Related Disease Conditions
Lower Back Pain
There are many causes of back pain. Pain in the low back can relate to the bony lumbar spine, discs between the vertebrae,...
Acute injuries, medical conditions, and chronic use conditions are causes of knee pain. Symptoms and signs that accompany knee...
Neck Pain (Cervical Pain)
Neck pain (cervical pain) may be caused by any number of disorders and diseases. Tenderness is another symptom of neck pain....
Tylenol Liver Damage
Tylenol liver damage (acetaminophen) can occur from accidentally ingesting too much acetaminophen, or intentionally. Signs and...
Chronic pain is pain (an unpleasant sense of discomfort) that persists or progresses over a long period of time. In contrast to...
Drug addiction is a chronic disease that causes drug-seeking behavior and drug use despite negative consequences to the user and...
Pain Management: Musculoskeletal Pain
Natural menopause is the permanent ending of menstruation that is not brought on by any type of medical treatment. For women...
Cancer pain results from the tumor pressing on nerves or invading bones or organs. Cancer treatments like chemotherapy,...
Myofascial Pain Syndrome
Myofascial pain syndrome is muscle pain in the body's soft tissues due to injury or strain. Symptoms include muscle pain with...
Drug-Induced Liver Disease
Drug-induced liver diseases are diseases of the liver that are caused by: physician-prescribed medications, OTC...
Pain management and treatment can be simple or complex, according to its cause. There are two basic types of pain, nociceptive...
Teen Drug Abuse
Drugs commonly abused by teens include tobacco products, marijuana, cold medications, inhalants, depressants, stimulants,...
Shoulder and Neck Pain
Shoulder and neck pain may be caused by bursitis, a pinched nerve, whiplash, tendinitis, a herniated disc, or a rotator cuff...
Kidney Pain (Location, Symptoms, Relief)
Kidney pain has a variety of causes and symptoms. Infection, injury, trauma, bleeding disorders, kidney stones, and less common...
Arthritis, bursitis, IT band syndrome, fracture, and strain are just some of the causes of hip pain. Associated symptoms and...
Treatment & Diagnosis
- Drug Interactions: Know Ingredients, Consult Your Physician
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Drugs: The Most Common Medication Errors
- Drugs: Buying Prescription Drugs Online Safely
- Medication Disposal
- Dangers of Mixing Medications
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
- acetaminophen (Tylenol, Tylenol Arthritis Pain, Tylenol Ext, Little Fevers Children's Fever/Pain)
- Oxycodone for Pain (OxyContin, Roxicodone, Oxecta, Oxaydo, Xtampza ER, Roxybond)
- fentanyl patch (Duragesic)
- Drugs: What You Should Know About Your Drugs
- Drug Interactions
- Oxycodone vs. Hydrocodone
- Oxycodone vs. Tramadol for Pain
- Percocet vs. Lortab for Pain
- Dilaudid vs. Oxycodone
- Oxycodone vs. Codeine
- Dilaudid vs. Percocet for Pain
- Acetaminophen vs. Ibuprofen for Pain (Differences in Side Effects and Dosage)
- Benzodiazepines vs. Narcotics (Opioids)
Prevention & Wellness
Quick GuideChronic Pain Syndrome: Treatment and Management for CPS
Pain Management Resources
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Top oxycodone and acetaminophen Related Articles
Cancer PainCancer pain results from the tumor pressing on nerves or invading bones or organs. Cancer treatments like chemotherapy, radiation, or surgery can also cause pain. Over-the-counter pain relievers, prescription medications, radiation, biofeedback, and relaxation techniques are just some treatments for cancer pain.
Chronic PainChronic pain is pain (an unpleasant sense of discomfort) that persists or progresses over a long period of time. In contrast to acute pain that arises suddenly in response to a specific injury and is usually treatable, chronic pain persists over time and is often resistant to medical treatments.
Drug AbuseDrug addiction is a chronic disease that causes drug-seeking behavior and drug use despite negative consequences to the user and those around him. Though the initial decision to use drugs is voluntary, changes in the brain caused by repeated drug abuse can affect a person's self-control and ability to make the right decisions and increase the urge to take drugs. Drug abuse and addiction are preventable.
Drug Abuse SlideshowWhat is drug abuse? Learn about prescription drug abuse and over-the-counter (OTC) drugs, including depressants, pain relievers, and stimulants.
Knee Pain FactsAcute injuries, medical conditions, and chronic use conditions are causes of knee pain. Symptoms and signs that accompany knee pain include redness, swelling, difficulty walking, and locking of the knee. To diagnose knee pain, a physician will perform a physical exam and also may order X-rays, arthrocentesis, blood tests, or a CT scan or MRI. Treatment of knee pain depends upon the cause of the pain.
Liver Blood TestsAn initial step in detecting liver damage is a simple blood test to determine the presence of certain liver enzymes in the blood. Under normal circumstances, these enzymes reside within the cells of the liver. But when the liver is injured, these enzymes are spilled into the blood stream, and can lead to diseases like fatty liver, type 2 diabetes, obesity, and hepatitis. Several medications also can increase liver enzyme test results.
Low Back PainThere are many causes of back pain. Pain in the low back can relate to the bony lumbar spine, discs between the vertebrae, ligaments around the spine and discs, spinal cord and nerves, muscles of the low back, internal organs of the pelvis and abdomen, and the skin covering the lumbar area.
Muscle PainMyofascial pain syndrome is muscle pain in the body's soft tissues due to injury or strain. Symptoms include muscle pain with tender points and fatigue. Treatment usually involves physical therapy, massage therapy, or trigger point injection.
Neck PainNeck pain (cervical pain) may be caused by any number of disorders and diseases. Tenderness is another symptom of neck pain. Though treatment for neck pain really depends upon the cause, treatment typically may involve heat/ice application, traction, physical therapy, cortisone injection, topical anesthetic creams, and muscle relaxants.
Pain Management: Musculoskeletal PainNatural menopause is the permanent ending of menstruation that is not brought on by any type of medical treatment. For women undergoing natural menopause, the process is described in three stages: perimenopause, menopause, and postmenopause. However, not all women undergo natural menopause. Some women experience induced menopause as a result of surgery or medical treatments, such as chemotherapy and pelvic radiation therapy.
Prescription Drug AbuseLearn about prescription drug abuse facts and statistics about the dangers and misconceptions of abusing common prescription drugs.
Tylenol Liver DamageTylenol liver damage (acetaminophen) can occur from accidentally ingesting too much acetaminophen, or intentionally. Signs and symptoms of acetaminophen-induced liver damage may include:
- kidney failure,
- bleeding disorders,
- coma, and