What Are the Side Effects of Glucosamine?

  • Medical Editor: William C. Shiel Jr., MD, FACP, FACR
    William C. Shiel Jr., MD, FACP, FACR

    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Ask the experts

In your articles about osteoarthritis, you mention that glucosamine chondroitin has helped to relieve symptoms of pain and stiffness for some people. Could you tell me what side effects can be expected from taking that food supplement? Also, could there be any interaction with Lescol?

Doctor's response

Glucosamine and chondroitin is generally very well tolerated. Possible side effects include upset stomach, skin rash, aggravation of pre-existing diabetes, and alteration of the effects of the blood-thinning drug warfarin (coumadin). I am not aware of any possible interaction with Lescol.

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Reviewed on 1/11/2018