Oncogene: 1. A gene that played a normal role in the cell as a proto-oncogene and that has been altered by mutation and now may contribute to the growth of a tumor.
Some of the more important oncogenes include:
- ras (a signal transduction molecule),
- myc (a transcription factor), src (a protein tyrosine kinase),
- HER-2/neu, also called erbB-2 (a growth factor receptor),
- hTERT (an enzyme involved in DNA replication), and
- Bcl-2 (a membrane associated protein that prevents apoptosis).
2. The name of the biomedical journal. Oncogene is a journal for researchers interested in the molecular biology of malignant change including molecular biologists, cell biologists, oncologists, geneticists and biotechnologists.
CONTINUE SCROLLING OR CLICK HERE
SLIDESHOW
Skin Cancer Symptoms, Types, Images See SlideshowHealth Solutions From Our Sponsors