GENERIC NAME: NYSTATIN/METRONIDAZOLE - VAGINAL INSERT (NYE-stat-in/meh-trow-NID-uh-zole)
HOW TO USE: This product is for vaginal use only. Using the applicator, insert one tablet deep into the vagina, once daily before bedtime for 10 days; or take as directed by your doctor. To help disintegration of the tablet, moisten the tablet with water before insertion. Insert the applicator high into the vagina and press the plunger to release the medication. After each use, clean the applicator with warm soapy water and rinse well. Continue to use this product until the full prescribed amount is finished even if symptoms disappear after a few days. Stopping the product too early may allow the bacteria/fungi to continue to grow, which may result in a relapse of the infection. If your symptoms worsen, or have not improved within 10 days, notify your doctor promptly. You may require additional medication to treat your condition. Your sexual partner may require medication to prevent re- infection. Consult your doctor.
SIDE EFFECTS: Vaginal burning/itching; gritty sensation in the vagina; bitter taste; stomach pain or nausea may occur. If any of these effects persist or worsen, notify your doctor promptly. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Tell your doctor your medical history, especially of: seizure disorders, liver disease, nervous system disorder, blood disorders, thyroid problems, adrenal problems, alcohol use, allergies (especially allergies to antibiotics or antifungals such as metronidazole or nystatin). Avoid drinking alcohol while using this product and for at least one day after finishing this product. Serious side effects such as vomiting, stomach pain, mental/mood changes and vision problems may occur. This product should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. The metronidazole in this product passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medication you may use, especially of: oral antibiotics or antifungals (e.g., metronidazole, nystatin), blood thinners (e.g., warfarin), phenytoin, lithium, disulfiram. Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. This product may be harmful if swallowed. Symptoms of overdose may include nausea and vomiting, loss of coordination, tingling or numbness of the fingers, or seizures.
NOTES: Do not share this product with others.
MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from light and moisture.
Related Disease Conditions
Vaginitis (Inflammation of the Vagina)
Vaginitis refers to inflammation of the vagina. Vaginitis can be caused by infections, menopause, or poor hygiene. Symptoms of vaginitis include vaginal itching, discharge, odor, pain, or discomfort. Treatment for vaginitis depends on the cause. Antibiotics may be necessary for some forms of vaginitis.
How Can I Treat Vaginitis at Home?
What Is Vaginitis? Learn whether you need antibiotics and what other treatments can help to relieve your symptoms.
Is Diverticulitis Contagious?
Diverticulitis is an inflammation of the diverticula or diverticulum. Diverticulitis causes are either infectious or noninfectious, however, it is not contagoius. Symptoms of diverticulitis include: nausea, vomiting, diarrhea, gas, constipation, changes in bowel habits, bloating, constipation, fever, abdominal tenderness, swollen abdomen, fistula formation, and lower left abdominal pain.
How Long Does it Take for a Vaginal Suppository to Absorb?
Vaginal suppositories take between 15 and 30 minutes to dissolve and get absorbed into the body. The absorption of a vaginal suppository depends on several factors, including the type of suppository, active ingredient, pH and moisture level of the vaginal environment, and the size and shape of the suppository. The time for the absorption process of a vaginal suppository to complete can vary widely and is difficult to determine.
Treatment & Diagnosis
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.