Generic drug: orphenadrine citrate, aspirin and caffeine
Brand name: Norgesic
What is Norgesic (orphenadrine citrate, aspirin and caffeine), and how does it work?
Norgesic belongs to a class of drugs called Analgesics, Other Combos.
It is not known if Norgesic is safe and effective in children younger than 12 years of age.
What are the side effects of Norgesic?
Norgesic may cause serious side effects including:
- mood changes,
- fast, pounding or irregular heartbeats,
- hearing changes (ringing in your ears, difficulty hearing),
- difficulty urinating,
- easy bruising or bleeding,
- black stools,
- vomit that looks like coffee grounds,
- persistent stomach or abdominal pain,
- eye pain,
- unusual tiredness,
- change in the amount of urine,
- yellowing of the eyes or skin (jaundice), and
- dark urine
Get medical help right away, if you have any of the symptoms listed above.
The most common side effects of Norgesic include:
- dry mouth,
- blurred vision,
- upset stomach,
- trouble sleeping, and
- increased urination
Tell the doctor if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of Norgesic. For more information, ask your doctor or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the dosage for Norgesic?
Norgesic Tablets: Adults 1 or 2 tablets 3 to 4 times daily.
Norgesic Forte Tablets: Adults ½ to 1 tablet 3 to 4 times daily.
Is Norgesic safe to use while pregnant or breastfeeding?
- Use of NSAIDs, including aspirin, can cause premature closure of the fetal ductus arteriosus and fetal renal dysfunction leading to oligohydramnios and, in some cases, neonatal renal impairment.
- Because of these risks, limit dose and duration of Norgesic and Norgesic Forte use between about 20 and 30 weeks of gestation, and avoid Norgesic and Norgesic Forte use at about 30 weeks of gestation and later in pregnancy.
- No information is provided regarding the effects of Norgesic on lactating women or breastfeeding infants.
Norgesic (orphenadrine citrate, aspirin and caffeine) is a prescription medicine used to treat the symptoms of musculoskeletal pain (muscle spasms). Serious side effects of Norgesic include mood changes, confusion, anxiety, hallucinations, nervousness, agitation, shaking, fast, pounding or irregular heartbeats, hearing changes (ringing in your ears, difficulty hearing), difficulty urinating, easy bruising or bleeding, black stools, vomit that looks like coffee grounds, and others.
Multimedia: Slideshows, Images & Quizzes
Pain Management: Surprising Causes of Pain
What’s causing your pain? Learn the common causes of lower back pain, as well as pain in the knee, stomach, kidney, shoulder,...
Lower Back Pain: Symptoms, Stretches, Exercise for Pain Relief
Do you suffer from low back pain? Learn more about common triggers of lower back pain like posture, exercise, and spondylosis....
Nerve Pain: Symptoms, Causes, and Treatment Options
Learn about nerve pain symptoms, causes, and treatment options. Discover medications and natural remedies to relieve nerve pain.
11 Exercises for Lower Back Pain Relief
One of the best low back pain treatments is exercise. Learn more about low back pain exercises--what works, and what doesn't....
Back Pain: 16 Back Pain Truths and Myths
Which mattress is best for back pain? Back pain conditions are very common. Learn the causes of upper and lower back pain. Find...
Pain-Relief Tips for Bumps, Bruises, Sprains, and Strains in Pictures
View this First Aid slideshow on Care and Pain Relief. See how to get pain relief if you've bumped your head, sprained your...
Pain Management: 15 Easy Ways to Reduce Chronic Pain
Chronic pain can be a symptom of many conditions, including arthritis, headaches, and others. Comprehensive pain management...
Pain Management: Signs Your Muscle Pain Is Something Else
Could your achy muscles be a sign of more than a tough workout? Learn when a twinge might warrant a visit to the doctor's office.
Back Pain: Bad Habits for Your Back
You’re more likely to have back pain as you get older. Here’s how to avoid making things worse with bad habits.
Neck Pain: Causes and Treatment for Relief
What causes chronic neck pain? If you have poor posture, bad sleep habits, or spine problems, these issues can lead to a stiff...
Back Pain: Common Spine Problems
That stack of little bones along the center of your back has a key role to support and control your body. What happens when...
Back Pain Quiz: Test Your Back Pain IQ
There are numerous causes of chronic lower back pain and only one ailment gets more complaints. What is it? Quiz your knowledge...
Pain Quiz: Test Your IQ of Pain
Is pain all in the brain? Take the Pain Quiz to learn everything you've ever wanted to know about the unpleasant sensation we...
Pain Management: All About CBD Oil
Cannabidiol oil: It's made from marijuana and everyone seems to be talking about it. But what is it, and what does it really do?
Pain Management: One-Move Fixes for Pain and Stress
A quick stretch, yoga pose, or on-the-spot exercise can help fix sudden aches from head to toe. Learn how to quash pain with just...
Back Pain: Tips for Traveling When You Have Back Pain
Don't let back or other pain keep you from your travel adventures. Try these tips to minimize discomfort during your next flight...
Pain Management: All About Your Knees
They do their job so well that you might take them for granted. Learn how they're put together, what can go wrong with them, and...
Back Pain: A Visual Guide to Herniated Disks
Have you felt pain shooting down your leg from your lower back or rear end? It may be that one of the disks that separate the...
Pain Management: Visual Guide to Frozen Shoulder
It's got nothing to do with cold weather. It means your shoulder is jammed up. WebMD guides you through the causes of frozen...
Pain Management: Ergonomic Tips for a Home Office
Are you working at home? Find out how to set up a workspace to prevent stiffness, protect your muscles and joints, and avoid...
Related Disease Conditions
Low Back Pain (Lumbar Spine Pain)
There are many causes of back pain. Pain in the low back can relate to the bony lumbar spine, discs between the vertebrae, ligaments around the spine and discs, spinal cord and nerves, muscles of the low back, internal organs of the pelvis and abdomen, and the skin covering the lumbar area.
Sciatica pain, caused by irritation of the sciatic nerve, typically radiates from the low back to behind the thigh to below the knee. Disc herniation is usually the cause of sciatica. Medication to alleviate pain, physical therapy, and bed rest are treatments for sciatica.
Neck Pain (Cervical Pain)
Neck pain (cervical pain) may be caused by any number of disorders and diseases. Tenderness is another symptom of neck pain. Though treatment for neck pain really depends upon the cause, treatment typically may involve heat/ice application, traction, physical therapy, cortisone injection, topical anesthetic creams, and muscle relaxants.
Reflex Sympathetic Dystrophy (RSD, Complex Regional Pain Syndrome Type 1, CRPS)
Reflex sympathetic dystrophy syndrome (RSD) is a condition that features atypical symptoms including pain (often "burning" type), tenderness, and swelling of an extremity associated with varying degrees of sweating, warmth and/or coolness, flushing, discoloration, and shiny skin. RSD is also referred to as "the shoulder-hand syndrome." Treatment response is greater in earlier stages than later stages.
Muscle Pain (Myofascial Pain Syndrome)
Muscle pain (myofascial pain syndrome) is muscle pain in the body's soft tissues due to injury or strain. Symptoms include muscle pain with tender points and fatigue. Treatment usually involves physical therapy, massage therapy, or trigger point injection.
Neck Pain and Dizziness
Neck pain is any degree of discomfort in the front or back of the neck between the head and the shoulders. Dizziness is characterized as either vertigo with disequilibrium or lightheadedness associated with feeling faint or the potential to lose consciousness. Causes of neck pain and dizziness vary, and treatment depends on the cause. With any unexplained or persisting neck pain or dizziness, consult with a health care professional, who can determine whether the symptoms are harmless and temporary or serious and threatening.
Neuropathic pain is a chronic condition that leads to ongoing pain symptoms. Patients can be predisposed to developing neuropathic pain who have conditions such as diabetes, cancer, stroke, HIV, vitamin deficiencies, shingles, and multiple sclerosis. Patient history and nerve testing are used to diagnose neuropathic pain. Antidepressants, antiseizure medications, and other types of medications are used to treat neuropathic pain. Many people with neuropathic pain are able to attain some level of relief.
How Do I Know if My Back Pain Is Kidney Related?
The pain of kidney infection may be felt on the sides (flanks) and the back. Unlike the classical back pain due to muscle or bone involvement, which typically affects the lower back, kidney pain is felt higher up and at a greater depth.
Chronic pain is pain (an unpleasant sense of discomfort) that persists or progresses over a long period of time. In contrast to acute pain that arises suddenly in response to a specific injury and is usually treatable, chronic pain persists over time and is often resistant to medical treatments.
Pain Management: Musculoskeletal Pain
Natural menopause is the permanent ending of menstruation that is not brought on by any type of medical treatment. For women undergoing natural menopause, the process is described in three stages: perimenopause, menopause, and postmenopause. However, not all women undergo natural menopause. Some women experience induced menopause as a result of surgery or medical treatments, such as chemotherapy and pelvic radiation therapy.
Myofascial Pain Syndrome Vs Fibromyalgia
Most people with chronic pain and fatigue in their muscles tend to have either fibromyalgia or myofascial pain syndrome (MPS). Fibromyalgia is a condition characterized by widespread musculoskeletal (involving the muscles and bones) pain accompanied by fatigue, sleep, memory, and mood issues.
Pain Relief Options for Childbirth
Women experience and tolerate pain differently. For some pregnant women, focused breathing is all they need to get through labor and childbirth; but for others, numbing of the pain is desired. There are a number of different medications a woman can take during labor and childbirth. It is important for you to learn what pain relief options are available. Please discuss the options with your health care provider well before your "birth day" so that when you are in labor you understand the choices.
Pain Management: Neuropathic Pain
Neuropathic pain is chronic pain resulting from injury to the nervous system. The injury can be to the central nervous system (brain and spinal cord) or the peripheral nervous system (nerves outside the brain and spinal cord).
What Is the Best Exercise for Back Pain?
We are often a bit negligent toward our back while doing chores or physical exercise. While the causes for back pain may vary, regular exercise and maintaining a healthy weight are crucial for keeping the back healthy.
Treatment & Diagnosis
- Muscle Pain (Myalgia)
- Neck Pain (Cervicalgia)
- Lower Back Pain
- Chronic Pain
- Chronic Pain: Implantable Pain Control Devices
- Pain Management
- Neuropathic Pain
- Chronic Pain and Fatigue - What You Can Do
- Pain Management: Painkiller Addiction
- Pain Awareness and Management
- Chronic Pain: Dealing With Back and Neck Pain
- Chronic Pain Treatments for Mind and Body
- Pain Management: Dealing with Back Pain
- Mind-Body-Pain Connection: How Does It Work?
- Pain: Managing the Pains and Aches of Office Life
- Meditation for Stress and Pain with Karen Eastman, Ph.D., Lobsang Rapgay, Ph.D., and Lonnie Zeltz
- Pain Management: Routes to Relief
- Back Pain FAQs
- Pain FAQs
- Pain and Stress: Endorphins: Natural Pain and Stress Fighters
- Pain Management: OTC NSAIDs - Doctors Dialogue
- Pain Management Over-The-Counter
- Myositis Muscle (Pain and Inflammation) Serious Drug Interactions
- Pain (Acute and Chronic)
- What Pain Medication Can I Take While on Warfarin?
- Sciatica Pain Vs. Fibromyalgia Pain: What Are The Differences?
- Does Pain Medication Affect Men and Women Differently?
- Pain Relievers and High Blood Pressure
Medications & Supplements
- aspirin (acetylsalicylic acid, Bayer, Ecotrin, and others)
- Aspirin vs. Plavix (clopidogrel)
- Aspirin vs. Eliquis (apixaban)
- Aspirin vs. Aleve (Naproxen)
- aspirin - oral, Easprin, Ecotrin
- aspirin chewable - oral, Children's Aspirin
- Aspirin vs. Tylenol (acetaminophen)
- Aspirin vs. NSAIDs (Side Effect and Use Differences)
- Aspirin vs. warfarin (Coumadin, Jantoven)
- orphenadrine (Norflex)
- orphenadrine - injection, Norflex
- Aspirin Therapy (Guidelines for Heart Attack and Stroke Prevention)
- orphenadrine/aspirin/caffeine - oral, Norgesic
- aspirin suppository - rectal
- Side Effects of Norflex (orphenadrine)
- aspirin gum - oral, Aspergum
Latest Medications News
Daily Health News
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.