Non-Hodgkin's lymphoma refers to a group of different cancers that begin in the cells of the immune system. In particular, these cancers originate in lymphocytes, a type of white blood cell. Lymphoma refers to any cancer that begins in these cells, and lymphomas are classified as Hodgkin's lymphoma or non-Hodgkin's lymphoma based on their appearance under the microscope and additional tests to characterize the cells.
Non-Hodgkin's lymphoma can arise almost anywhere in the body. Signs and symptoms of non-Hodgkin's lymphoma can vary but may include painless, swollen lymph nodes in the neck, armpits, or groin. Other associated symptoms can include
- abdominal pain or swelling,
- chest pain,
- coughing or trouble breathing,
- persistent fatigue,
- fever,
- night sweats, and
- unexplained weight loss.
Cause of non-Hodgkin's lymphoma
Doctors don't know the exact cause of non-Hodgkin's lymphoma.
Other non-hodgkin's lymphoma symptoms and signs
- Abdominal Pain or Swelling
- Chest Pain
- Coughing or Trouble Breathing
- Fever
- Night Sweats
- Painless, Swollen Lymph Nodes in the Neck, Armpits, or Groin
- Persistent Fatigue
- Unexplained Weight Loss
Main Article on Non-Hodgkin's Lymphoma Symptoms and Signs

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Examples of Medications for Non-Hodgkin's Lymphoma Symptoms and Signs
- Aliqopa (copanlisib)
- Brukinsa (zanubrutinib)
- cyclophosphamide (Cytoxan)
- ibritumomab tiuxetan - injection, Zevalin
- Leukeran (chlorambucil)
- Matulane (procarbazine hydrochloride)
- Monjuvi (tafasitamab-cxix)
- nivolumab
- pembrolizumab
- prednisone
- rituximab (Rituxan)
- Valchlor (mechlorethamine)
- Xpovio (selinexor)
- Yescarta (axicabtagene ciloleucel)
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