Non-Celiac Gluten Sensitivity: Symptoms & Signs

Medically Reviewed on 9/10/2019

Non-celiac gluten sensitivity is a reduction in certain symptoms after gluten-containing foods are removed from the diet, in people who do not have true celiac disease. Celiac disease is an autoimmune disease that affects less than 1% of the population. Celiac disease causes a true immune reaction to gluten. Many people who do not have this condition, however, claim that they experience symptoms from gluten in foods.

Some of the symptoms and signs people report as related to gluten sensitivity include headache, brain fog, nausea, diarrhea, constipation, bloating, abdominal pain, and tingling or numbness in the fingers, legs, or arms. The associated symptoms arise within hours or days of consuming foods that contain gluten.

Cause of non-celiac gluten sensitivity

The cause of non-celiac gluten sensitivity is unclear.

Other non-celiac gluten sensitivity symptoms and signs

Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.