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What is nicardipine? What are the uses for nicardipine?
Nicardipine (Cardene, Cardene SR) belongs to a class of drugs referred to as calcium channel blockers (CCBs). Nicardipine is prescribed for the treatment of high blood pressure (hypertension) and angina (heart pain).
What brand names are available for nicardipine?
Cardene, Cardene SR
Is nicardipine available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for nicardipine?
What are the side effects of nicardipine?
Side effects include:
Fainting, over growth of the gums, and rash also may occur. It may increase heart rate due to a drop in blood pressure. Nicardipine sometimes causes an increase in the frequency and duration of angina. The reason for this side effect is not clearly understood. Excessively low blood pressure can occur in rare instances, especially during initiation of treatment or following adjustments of dosage.
What is the dosage for nicardipine?
The recommended dose of nicardipine for treatment of hypertension is 20-40 mg three times daily with conventional capsules or 30-60 mg twice daily with sustained release capsules. Intravenous infusion rates can range between 0.5 and 15 mg/hr. Chest pain is treated with 20-40 mg of conventional capsules three times daily.
Which drugs or supplements interact with nicardipine?
Rifampin, phenobarbital, phenytoin (Dilantin, Dilantin-125), oxcarbazepine (suspension oral Trileptal; oral Trileptal) and carbamazepine (Tegretol, Tegretol XR , Equetro, Carbatrol) may reduce blood levels of nicardipine by increasing its metabolism (destruction) in the liver. Therapy should be monitored and drug doses should be adjusted accordingly when nicardipine is used with these drugs.
Co-administration of nicardipine and cyclosporine results in increased cyclosporine blood levels. Cyclosporine blood levels should be monitored and its dosage reduced when taking nicardipine.
Is nicardipine safe to take if I'm pregnant or breastfeeding?
What else should I know about nicardipine?
What preparations of nicardipine are available?
Capsules: 20 and 30 mg; Sustained release capsules:30 and 60 mg; Injection 0.1, 0.2 and 2.5 mg
How should I keep nicardipine stored?
Nicardipine should be stored at room temperature, 15 C to 30 C (59 F to 86 F), and protected from light.
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Nicardipine (Cardene, Cardene SR) belongs to a class of drugs referred to as calcium channel blockers (CCBs). Nicardipine is prescribed for the treatment of high blood pressure and angina (heart pain). Side effects, drug interactions, warnings and precautions, and patient information should be reviewed prior to taking any medication.
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Related Disease Conditions
Angina is chest pain due to inadequate blood supply to the heart. Angina symptoms may include chest tightness, burning, squeezing, and aching. Coronary artery disease is the main cause of angina but there are other causes. Angina is diagnosed by taking the patient's medical history and performing tests such as an electrocardiogram (EKG), blood test, stress test, echocardiogram, cardiac CT scan, and heart catheterization. Treatment of angina usually includes lifestyle modification, medication, and sometimes, surgery. The risk of angina can be reduced by following a heart healthy lifestyle.
High Blood Pressure (Hypertension) Signs, Causes, Diet, and Treatment
High blood pressure (hypertension) is a disease in which pressure within the arteries of the body is elevated. About 75 million people in the US have hypertension (1 in 3 adults), and only half of them are able to manage it. Many people do not know that they have high blood pressure because it often has no has no warning signs or symptoms. Systolic and diastolic are the two readings in which blood pressure is measured. The American College of Cardiology released new guidelines for high blood pressure in 2017. The guidelines now state that blood normal blood pressure is 120/80 mmHg. If either one of those numbers is higher, you have high blood pressure. The American Academy of Cardiology defines high blood pressure slightly differently. The AAC considers 130/80 mm Hg. or greater (either number) stage 1 hypertension. Stage 2 hypertension is considered 140/90 mm Hg. or greater. If you have high blood pressure you are at risk of developing life threatening diseases like stroke and heart attack.REFERENCE: CDC. High Blood Pressure. Updated: Nov 13, 2017.
Raynaud's phenomenon is characterized by a pale-blue-red sequence of color changes of the digits, most commonly after exposure to cold. Occurring as a result of spasm of blood vessels, the cause is unknown. Symptoms of Raynaud's phenomenon depend on the severity, frequency, and duration of the blood vessel spasm. Treatments include protection of the digits, medications, and avoiding emotional stresses, smoking, cold temperature, and tools that vibrate the hands.
Scleroderma is an autoimmune disease of the connective tissue. It is characterized by the formation of scar tissue (fibrosis) in the skin and organs of the body, leading to thickness and firmness of involved areas. Scleroderma is also referred to as systemic sclerosis, and the cause is unknown. Treatment of scleroderma is directed toward the individual features that are most troubling to the patient.
Preeclampsia (Pregnancy Induced Hypertension)
Preeclampsia is related to increased blood pressure and protein in the mother's urine. Preeclampsia typically begins after the 20th week of pregnancy. When preeclampsia causes seizures, it is termed "eclampsia" and is the second leading cause of maternal death of in the US. Preeclampsia is the leading cause of fetal complications. Risk factors for preeclampsia include high blood pressure, obesity, multiple births, and women with preexisting medical conditions such as diabetes, kidney disease, rheumatoid arthritis, lupus, or scleroderma. Pregnancy planning and lifestyle changes may reduce the risk of preeclampsia during pregnancy.
Preeclampsia and Eclampsia
Preeclampsia is a condition in pregnant women marked by high blood pressure and a high level of protein in the urine. Eclampsia occurs when preeclampsia goes untreated. Eclampsia can cause coma and death of the mother and baby. Preeclampsia symptoms include rapid weight gain, abdominal pain, headaches, blood in the urine, dizziness, and excessive vomiting and nausea. The only real cure for preeclampsia and eclampsia is the birth of the baby.
High Blood Pressure Treatment (Natural Home Remedies, Diet, Medications)
High blood pressure (hypertension) means high pressure (tension) in the arteries. Treatment for high blood pressure include lifestyle modifications (alcohol, smoking, coffee, salt, diet, exercise), drugs and medications such as ACE inhibitors, angiotensin receptor blockers, beta blockers, diuretics, calcium channel blockers (CCBs), alpha blockers, clonidine, minoxidil, and Exforge.
Chest pain is a common complaint by a patient in the ER. Causes of chest pain include broken or bruised ribs, pleurisy, pneumothorax, shingles, pneumonia, pulmonary embolism, angina, heart attack, costochondritis, pericarditis, aorta or aortic dissection, and reflux esophagitis. Diagnosis and treatment of chest pain depends upon the cause and clinical presentation of the patient's chest pain.
Heart disease (coronary artery disease) occurs when plaque builds up in the coronary arteries, the vessels that supply blood to the heart. Heart disease can lead to heart attack. Risk factors for heart disease include: Smoking High blood pressure High cholesterol Diabetes Family history Obesity Angina, shortness of breath, and sweating are just a few symptoms that may indicate a heart attack. Treatment of heart disease involves control of heart disease risk factors through lifestyle changes, medications, and/or stenting or bypass surgery. Heart disease can be prevented by controlling heart disease risk factors.
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.