Neuropathic Pain: Symptoms & Signs

Medically Reviewed on 4/22/2020

Neuropathic pain is not a disease itself, rather it is a term used to describe pain originating from the sensory nerves. It tends to develop slowly over time and persist.

Signs and symptoms of neuropathic pain can vary in severity even within one affected individual. Symptoms can include a

  • stabbing, burning, shooting pain;
  • tingling;
  • numbness; or a
  • pins and needles feeling.

The pain is sometimes described as sharp, dull, hot, cold, sensitive, deep, stinging, or itchy.

Cause of neuropathic pain

A number of conditions that affect or damage the nerves can cause neuropathic pain. Examples of conditions that can cause neuropathic pain include diabetes, cancer, HIV infection, multiple sclerosis, cancer treatments, vitamin deficiencies, stroke, alcohol abuse, and shingles.

Other neuropathic pain symptoms and signs

  • Numbness
  • Pins and Needles Sensation
  • Stabbing, Burning, or Shooting Pain
  • Tingling


Acanthosis Nigricans Browse through our medical image collection to see and discover unique diseases and conditions See Images

Subscribe to MedicineNet's General Health Newsletter

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.