- What is neomycin-polymyxin-hydrocortisone-otic suspension (Cortisporin, Otimar, Pediotic)? How does it work (mechanism of action)?
- What are the side effects of Cortisporin, Otimar, and Pediotic octic suspension?
- What is the dosage for Cortisporin, Otimar, and Pediotic otic suspension?
- Which drugs or supplements interact with Cortisporin, Otimar, and Pediotic otic suspension?
- Is Cortisporin, Otimar, and Pediotic otic suspension safe to take if you are pregnant or breastfeeding?
- What else should you know about neomycin-polymyxin-hydrocortisone-otic suspension?
What is neomycin-polymyxin-hydrocortisone-otic suspension (Cortisporin, Otimar, Pediotic)? How does it work (mechanism of action)?
Neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate is an antibacterial and anti-inflammatory ear drop. Neomycin and polymyxin are antibiotics that are active against gram positive and gram negative bacteria like Staphylococcus aureus, Escherichia coli, Haemophilus influenzae, Klebsiella-Enterobacter species, Neisseria species, and Pseudomonas aeruginosa. Neomycin inhibits protein synthesis in bacteria, leading to bacterial cell death. Polymyxin alters bacterial cell wall structure so that cellular contents leak out and causes the bacteria to die. Hydrocortisone suppresses inflammation in the affected area. The
- FDA approved neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate in March, 1957.
- Brand names for neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate are Cortisporin, Otimar, and Pediotic.
- Neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate is available in generic form. You need a prescription to obtain the drug.
What is the dosage for Cortisporin, Otimar, and Pediotic otic suspension?
- Adults: Apply 4 drops into affected ear every 6 to 8 hours.
- Infants and children: Apply 3 drops into affected ear every 6 to 8 hours.
- The duration of treatment may last up to 10 days.
Which drugs or supplements interact with Cortisporin, Otimar, and Pediotic otic suspension?
There are no significant drug interactions with neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate.
SLIDESHOW
Heart Disease: Causes of a Heart Attack See SlideshowIs Cortisporin, Otimar, and Pediotic otic suspension safe to take if you are pregnant or breastfeeding?
There are no adequate studies done with neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate to determine if it is safe and effective in pregnant women.
It is not known whether neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate enters breast milk; therefore, it is best to be cautious before using it in females who are breastfeeding.
What else should you know about neomycin-polymyxin-hydrocortisone-otic suspension?
What preparations of neomycin-polymyxin-hydrocortisone-otic suspension are available?
Neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate ear drops are available in sterile suspension and solution forms in 10 ml bottles.
How should I keep neomycin-polymyxin-hydrocortisone-otic suspension stored?
Neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate ear drops should be stored between 15 C to 25 C (59 F to 77 F).
Summary
Neomycin sulfate, polymyxin B sulfate, hydrocortisone acetate (Cortisporin, Otimar, Pediotic) is a prescription anti-inflammatory and antibacterial eardrop prescribed to treat bacterial infections of the external ear canal. Side effects, drug interactions, dosage, storage, and pregnancy safety information should be reviewed prior to taking this medication.
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.