Multiple myeloma is a form of cancer that develops in plasma cells, the white blood cells that make antibodies. Symptoms include bone pain, weakness, extreme thirst, nausea, frequent urination, and broken bones. Treatment of multiple myeloma depends upon the staging and symptoms of the disease. Read more: Multiple Myeloma Article
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Related Disease Conditions
Kidney (Renal) Failure
Kidney failure can occur from an acute event or a chronic condition or disease. Prerenal kidney failure is caused by blood loss, dehydration, or medication. Some of the renal causes of kidney failure include sepsis, medications, rhabdomyolysis, multiple myeloma, and acute glomerulonephritis. Post renal causes of kidney failure include bladder obstruction, prostate problems, tumors, or kidney stones.Treatment options included diet, medications, or dialysis.
Anemia: Symptoms, Treatment and Causes
Anemia is the condition of having less than the normal number of red blood cells or less than the normal quantity of hemoglobin in the blood. The oxygen-carrying capacity of the blood is, therefore, decreased. There are several types of anemia such as iron deficiency anemia (the most common type), sickle cell anemia, vitamin B12 anemia, pernicious anemia, and aplastic anemia. Symptoms of anemia may include fatigue, malaise, hair loss, palpitations, menstruation, and medications. Treatment for anemia includes treating the underlying cause for the condition. Iron supplements, vitamin B12 injections, and certain medications may also be necessary.
Cancer is a disease caused by an abnormal growth of cells, also called malignancy. It is a group of 100 different diseases, and is not contagious. Cancer can be treated through chemotherapy, a treatment of drugs that destroy cancer cells.
Low Back Pain (Lumbar Spine Pain)
There are many causes of back pain. Pain in the low back can relate to the bony lumbar spine, discs between the vertebrae, ligaments around the spine and discs, spinal cord and nerves, muscles of the low back, internal organs of the pelvis and abdomen, and the skin covering the lumbar area.
Fever in Adults and Children
Although a fever technically is any body temperature above the normal of 98.6 F (37 C), in practice, a person is usually not considered to have a significant fever until the temperature is above 100.4 F (38 C). Fever is part of the body's own disease-fighting arsenal; rising body temperatures apparently are capable of killing off many disease-producing organisms.
Constipation is defined medically as fewer than three stools per week and severe constipation as less than one stool per week. Constipation usually is caused by the slow movement of stool through the colon. There are many causes of constipation including medications, poor bowel habits, low-fiber diets, laxative abuse, and hormonal disorders, and diseases primarily of other parts of the body that also affect the colon.
Bone cancer is a rare type of cancer that occurs in cells that make up the bones. Primary bone cancer that arises in bone cells is different than metastatic bone cancer, which is cancer that arises in another part of the body and then spreads to the bones. Hereditary and environmental factors likely contribute to the risk of bone cancer. Signs and symptoms of bone cancer may include pain, the presence of a mass or lump, and bone fractures. There are different types of bone cancer (osteosarcoma, chondrosarcoma, Ewing's sarcoma, pleomorphic sarcoma, fibrosarcoma). Treatment for bone cancer may include surgical removal of the tumor, chemotherapy, radiation, and/or a stem cell transplant. The prognosis for bone cancer depends on the type of cancer and the extent of spread.
Nausea and Vomiting
Nausea is an uneasiness of the stomach that often precedes vomiting. Nausea and vomiting are not diseases, but they are symptoms of many conditions. There are numerous cases of nausea and vomiting. Some causes may not require medical treatment, for example, motion sickness, and other causes may require medical treatment by a doctor, for example, heart attack, lung infections, bronchitis, and pneumonia. Some causes of nausea and vomiting may be life-threatening, for example, heart attack, abdominal obstruction, and cancers. Treatment of nausea and vomiting depends upon the cause.
A broken bone is a fracture. There are different types of fractures, such as: compressed, open, stress, greenstick, spiral, vertebral compression, compound, and comminuted. Symptoms of a broken bone include pain at the site of injury, swelling, and bruising around the area of injury. Treatment of a fracture depends on the type and location of the injury.
Cancer Risk Factors and Causes
Though it's difficult to say why some people develop cancer while others don't, research shows that certain risk factors increase a person's odds of developing cancer. These risk factors include growing older, family history of cancer, diet, alcohol and tobacco use, and exposure to sunlight, ionizing radiation, certain chemicals, and some viruses and bacteria.
Multiple Myeloma: Deadly to Chronic
Multiple myeloma is cancer of the plasma cells. The plasma cells are a type of white blood cell present in the bone marrow. Plasma cells are part of the immune system and help fight against infections by producing antibodies that recognize and attack microorganisms. In multiple myeloma, cancer cells accumulate in the bone marrow and replace healthy blood cells.
Vasculitis (arteritis, angiitis) is a general term for a group of uncommon diseases which feature inflammation of the blood vessels. Each form of vasculitis has its own characteristic pattern of symptoms. The diagnosis of vasculitis is definitively established after a biopsy of involved tissue demonstrates the pattern of blood vessel inflammation. Treatment is directed toward decreasing the inflammation of the arteries and improving the function of affected organs.
Amyloidosis is a group of diseases resulting from abnormal deposition of certain proteins (amyloids) in various bodily areas. The amyloid proteins may either be deposited in one particular area of the body (localized amyloidosis) or they may be deposited throughout the body (systemic amyloidosis). There are three types of systemic amyloidosis: primary (AL), secondary (AA), and familial (ATTR). Primary amyloidosis is not associated with any other diseases and is considered a disease entity of its own. Secondary amyloidosis occurs as a result of another illness. Familial Mediterranean Fever is a form of familial (inherited) amyloidosis. Amyloidosis treatment involves treating the underlying illness and correcting organ failure.
Tumor grade is a system used to classify cancer cells in how likely the tumor is to grow and how abnormal they look under a microscope. Tumor grade is not the same as tumor stage. A biopsy is taken to determine if the tumor is benign (non cancerous) or malignant (cancerous).
Hypercalcemia (Elevated Calcium Levels)
Hypercalcemia is a condition in which calcium levels in the blood are elevated. Hypercalcemia is associated with other conditions such as hyperparathyroidism, lung cancer, breast cancer, kidney failure, and elevated levels of vitamin D. Symptoms of hypercalcemia include constipation, nausea, abdominal pain, and kidney stones. Treatment depends on the cause of hypercalcemia.
Carpal Tunnel Syndrome
Carpal tunnel syndrome is a condition in which irritation of the wrist's median nerve causes tingling and numbness of the thumb, index, and the middle fingers. Treatment of carpal tunnel syndrome depends on the severity of the symptoms and the nature of any disease that might be causing the symptoms.
Cancer fatigue is a lack of energy that is caused by cancer or cancer treatment, including chemotherapy, radiation, biological therapy, or bone marrow transplantation. Strategies to combat cancer fatigue include scheduling rest, pacing oneself, planning ahead and prioritizing work and activities, eating the right foods, exercising, and practicing proper body mechanics.
Certain behavioral, lifestyle, and environmental factors contribute to cancer. Cancer prevention involves modifying these factors to decrease cancer risk. Tobacco use, alcohol consumption, physical inactivity, inadequate fruit and vegetable intake, and obesity increase the risk of certain cancers. Vaccines, genetic testing, and cancer screening also play a role in cancer prevention.
Cancer pain results from the tumor pressing on nerves or invading bones or organs. Cancer treatments like chemotherapy, radiation, or surgery can also cause pain. Over-the-counter pain relievers, prescription medications, radiation, biofeedback, and relaxation techniques are just some treatments for cancer pain.
Multiple Myeloma: Types of Treatment
Multiple myeloma is a cancer of the plasma cells. The plasma cells are a type of white blood cell present in the bone marrow. Plasma cells are part of the immune system and help fight against infections by producing antibodies that recognize and attack microorganisms.
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Treatment & Diagnosis
- Complete Blood Count (CBC): Test, Types, Ranges, and Chart
- C-Reactive Protein (CRP) Test and Levels
- How Long a Person Can Live With Multiple Myeloma?
- MRI (Magnetic Resonance Imaging Scan)
- Pneumococcal Vaccination (Pneumonia Vaccine)
- Sedimentation Rate
- CT Scan (Computerized Tomography)
- Apheresis (Hemapheresis, Pheresis)
- Bone Marrow Aspiration and Biopsy
- Radiation Therapy
- Screening Tests for Cancer
- Is Multiple Myeloma Cancer Curable?
- Peripheral Blood Stem Cell Transplantation
- Weight Loss
- Leg Swelling
- Loss of Appetite
- Fatigue, Tiredness, and Lethargy
- Low Urine Output
- Frequent Urination
- Swollen Tongue
- Lower Back Pain
- Decreased Appetite
- Multiple Myeloma
- Doctor: Checklist to Take To Your Doctor's Appointment
- How to Choose a Doctor
- Doctor: Getting the Most from Your Doctor's Appointment
- Advance Medical Directives
- Cancer FAQs
- Multiple Myeloma FAQs
- Coping with a Bad Disease - Community Counts
- What Is a Hospitalist?
- Is Multiple Myeloma the Same as Leukemia?
- How Common Is Multiple Myeloma?
- Is Multiple Myeloma Curable?
- How Many Stages of Multiple Myeloma Are There?
- What Is the Life Expectancy of Someone with Multiple Myeloma?
- What Is Bone Cancer?
- Weight Gain, Obesity & Cancer Risk
Medications & Supplements
- Monoclonal Antibodies
- prednisone (Prednisone Intensol, Rayos) Corticosteroid
- alendronate, Fosamax, Binosto
- bortezomib - injection, Velcade
- lenalidomide (Revlimid)
- cyclophosphamide (Cytoxan)
- thalidomide (Thalomid)
- vincristine - injection, Oncovin
- doxorubicin - injection, Adriamycin, Rubex
- Fosamax (alendronate) Side Effects, Warnings, and Drug Interactions
- Types of Multiple Myeloma Medications
- Pomalyst (pomalidomide)
- Side Effects of Darzalex (daratumumab)
- Darzalex Faspro (daratumumab and hyaluronidase-fihj)
- daratumumab (Darzalex)
- Side Effects of Revlimid (lenalidomide)
- Side Effects of Thalomid (thalidomide)
- Ninlaro (ixazomib)
- melphalan - oral, Alkeran
- Pepaxto (melphalan flufenamide)
- Hemady (dexamethasone)
- Kyprolis (carfilzomib)
- Xpovio (selinexor)
Prevention & Wellness
- Some Myeloma Patients Get No Protection From COVID-19 Vaccines
- Sarclisa Approved for Treatment of Multiple Myeloma
- Gene Editing Tool Used to Fight Cancer in Early Study
- Study Uncovers Racial Gaps in Treatment of Multiple Myeloma
- Drug Offers Hope Against a Tough-to-Treat Blood Cancer
- FDA Approves Inrebic Capsules for Myelofibrosis
- Xpovio With Dexamethasone Approved for Refractory Multiple Myeloma
- Gene Therapy May Help Fight Tough-to-Treat Blood Cancer
- Many Ground Zero Rescue Workers Battling Cancer Years Later
- Gene-Based Therapy May Thwart a Tough Blood Cancer
- Powerful Drug for Advanced Cancers May Need Less Frequent Dosing
- Therapeutic Vaccine Shows 'Game-Changing' Promise Against a Leukemia
- Drug Trio Shows Major Promise Against Myeloma
- Excess Weight Tied to Higher Risk for Many Cancers, Experts Say
- Superior Results for Myeloma Drug That's Added Earlier in Treatment
- Empliciti Approved for Multiple Myeloma
- Ninlaro Approved for Multiple Myeloma
- Darzalex Approved for Multiple Myeloma
- Experimental Drug for Blood Cancer Shows Promise
- New Drug Shows Potential for Blood Cancer
- Farydak Approved for Multiple Myeloma
- Newer Drug Helps Myeloma Patients Who Can't Have Transplant
- Health Highlights: May 16, 2014
- Newsman Tom Brokaw Has Many Treatment Options for His Blood Cancer
- Newsman Tom Brokaw Battling Blood Cancer
- Report Sees Continued Advances in War Against Cancer
- Pomalyst Approved for Advanced Multiple Myeloma
- Drug Shows Promise for Lupus Skin Conditions
- Kyprolis Approved for Multiple Myeloma
- New Drug Shows Promise for Myeloma Patients
- Why Cancer Symptoms May Elude M.D.
- Health Highlights: Feb. 21, 2012
- FDA Moves to Head Off Shortages of 2 Cancer Drugs
- 9/11 Responders May Be At Raised Myeloma Risk
- Thalidomide Improves Outcomes for Older Myeloma Patients
- Experts Outline Use of Bisphosphonates Against Myeloma
- Drug Combos Team Up Against Myeloma