Mood swings refer to rapid changes in mood. The term may refer to minor daily mood changes or to significant mood changes as seen with mood disorders such as major depression or bipolar depression. Mood swings can also occur in women who suffer from premenstrual syndrome or premenstrual dysphoric disorder. The menopausal transition, specifically the time around approaching menopause or perimenopause, is associated with mood swings in some women. Mood swings can be seen with other conditions as well, including schizophrenia, attention deficit hyperactivity disorder, dementia, and thyroid conditions.
Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.
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Other Causes of Mood Swings
- Cyclothymic Disorder
- Intermittent Explosive Disorder
Examples of Medications for Mood Swings
- bupropion (Wellbutrin, Wellbutrin SR, Wellbutrin XL, Zyban, Aplenzin, Fortivo XL, Zyban)
- citalopram, Celexa
- desvenlafaxine (Pristiq, Khedezla)
- duloxetine, Cymbalta
- flibanserin (Addyi)
- fluoxetine, Prozac, Sarafem, Prozac Weekly
- fluvoxamine (Luvox and Luvox CR have been discontinued)
- Lexapro (escitalopram)
- lithium, Lithobid
- mirtazapine, Remeron, Soltab
- nefazodone, Serzone
- paroxetine, Paxil, Paxil CR, Pexeva
- trazodone (Desyrel - discontinued brand)
- venlafaxine, Effexor XR (Effexor has been discontinued in the US)
- Zoloft (sertraline)