Monkeypox (Mpox): Symptoms & Signs

Medically Reviewed on 11/29/2022

Monkeypox (mpox) is a rare illness similar to smallpox that occurs primarily in the rainforest countries of Central and West Africa.

Signs and symptoms of monkeypox infection include

Cause of Monkeypox

Infection with the monkeypox virus causes monkeypox. The viral infection has been described in laboratory monkeys, African tree squirrels, mice, rats, and rabbits, and the monkeypox virus can spread to humans from an infected animal through an animal bite or direct contact with the animal's lesions or bodily fluids. It can also spread from person to person.

Other monkeypox symptoms and signs

  • Backache
  • Enlargement of Lymph Nodes (Lymphadenopathy)
  • Exhaustion
  • Fever
  • General Feeling of Discomfort
  • Headache
  • Muscle Aches
  • Papular Skin Rash (Raised Bumps), Often First on the Face but Sometimes Initially on Other Parts of the Body
  • Swollen Lymph Nodes


Bowel regularity means a bowel movement every day. See Answer

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Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.