GENERIC NAME: MOCLOBEMIDE - ORAL TABLET (mow-KLO-bem-ide)
HOW TO USE: Take this medication by mouth immediately after meals as prescribed. Your dose may be adjusted gradually during the first weeks of therapy to find the dose just right for you. Follow dosing instructions closely. Do not take this more often, increase your dose or stop taking this without first consulting your doctor.
SIDE EFFECTS: This medication may initially cause dizziness, nervousness, mild headache, trouble sleeping and nausea as your body adjusts to the medication. Other side effects reported include sweating, loss of appetite, dry mouth, anxiety or blurred vision. If any of these effects continue or become bothersome, inform your doctor. To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly. Notify your doctor if you develop: rapid/pounding/irregular heartbeat, stomach pain, chest pain, sudden and severe headache, stiff neck, confusion, disorientation, slurred speech, behavioral changes, fever, skin rash. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Tell your doctor if you have: kidney problems, liver disease, thyroid disease, high blood pressure, allergies (especially drug allergies). Use caution when driving or operating machinery if this medication makes you drowsy or dizzy. Avoid excessive amounts of alcohol while taking this medication. Depending on your medical history, your doctor may choose to restrict your dietary intake of tyramine during and for 2 weeks following discontinuing the use of moclobemide. Certain foods and beverages are high in tyramine. Consult your doctor or pharmacist for details if needed. Though uncommon, depression itself can lead to thoughts or attempts of suicide. Tell your doctor immediately if you have any suicidal thoughts, or other mental/mood changes. Keep all medical appointments so your doctor can monitor your progress closely. This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Small amounts of this medication appear in breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: This drug should not be used with the following medications because very serious interactions may occur: apraclonidine, brimonidine, bethanidine, bupropion, buspirone, carbamazepine, dextromethorphan, entacapone, herbal products (e.g., ma huang), indoramin, meperidine, papaverine, sibutramine, SSRI antidepressants (e.g., fluoxetine, citalopram), sympathomimetics (e.g., methylphenidate, ephedrine), tolcapone, tricyclic antidepressants (e.g., amitriptyline, doxepin), "triptans" (e.g., sumatriptan, zolmitriptan). If you are currently using any of these medications, tell your doctor or pharmacist before starting moclobemide. Before using this medication, tell your doctor of all the medicines you use (both prescription and nonprescription), especially of: levodopa, insulin and oral diabetes drugs, other MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, tranylcypromine), sedatives, sleeping pills, blood pressure drugs. Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include disorientation and fast heartbeat or breathing.
NOTES: Laboratory tests may be done periodically while taking this medication to monitor the effects.
MISSED DOSE: Try to take each dose at the scheduled time. If you miss a dose, take it as soon as remembered; do not take it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.
STORAGE: Store this medication between 15 and 30 degrees C (59 to 86 degrees F) away from heat and light. Do not store in the bathroom. Keep this and all medications out of the reach of children.
MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).
Related Disease Conditions
Depression is an illness that involves the body, mood, and thoughts and affects the way a person eats and sleeps, the way one feels about oneself, and the way one thinks about things. The principal types of depression are major depression, dysthymia, and bipolar disease (also called manic-depressive disease).
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