- What is miconazole, and how does it work (mechanism of action)?
- What brand names are available for miconazole?
- Is miconazole available as a generic drug?
- Do I need a prescription for miconazole?
- What are the side effects of miconazole?
- What is the dosage for miconazole?
- Which drugs or supplements interact with miconazole?
- Is miconazole safe to take if I'm pregnant or breastfeeding?
- What else should I know about miconazole?
What is miconazole, and how does it work (mechanism of action)?
Miconazole is an anti-fungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). It is used either on the skin or in the vaginal for fungal infections. Miconazole was approved by the FDA in 1974.
What is the dosage for miconazole?
Miconazole vaginal cream and suppositories are for use only in the vagina. These products are not to be taken by mouth. The vaginal suppositories are inserted, one per dose, in an applicator. Alternatively, the tube containing the vaginal cream is screwed onto the end of a special applicator tube, and the tube is then squeezed to fill the applicator. The patient then lies on her back with bent knees, inserts the applicator containing either the suppository or cream so that the tip of the applicator is high in the vagina, and then pushes the plunger in to deposit the suppository or cream into the vagina. The applicator should be washed with warm soap and water after each use.
Miconazole usually is used once daily at bedtime. The 200 mg suppositories (Monistat 3) are inserted once nightly for 3 nights. The 100 mg suppositories (Monistat-7) and intravaginal cream are inserted once nightly for 7 nights. The 1200 mg formulation (Monistat 1) is applied once for one night.
For fungal skin infections, the topical cream is applied as a thin layer to cover the affected skin and surrounding area, usually once or twice daily for 2-4 weeks. The hands should be washed before and after application.
Which drugs or supplements interact with miconazole?
There are no known drug interactions with vaginal or topical miconazole.
Is miconazole safe to take if I'm pregnant or breastfeeding?
There is very limited information on the use of miconazole during pregnancy. The physician must weigh the potential benefits against possible but unknown risks to the fetus.
It is not known if miconazole is secreted in breast milk in amounts that can affect the infant.
What else should I know about miconazole?
What preparations of miconazole are available?
Preparations are as follows:
- Vaginal suppositories: 100 and 200 mg;
- Vaginal cream: 2 and 4%;
- Topical cream, aerosol powder, spray or tincture: 2%.
- Combination Packs: 100, 200, or 1200 mg suppository plus 2% vaginal cream.
How should I keep miconazole stored?
All formulations should be stored at room temperature, 15 C to 30 C (59 F TO 86 F).
Medically reviewed by Eni Williams; PharmD., Ph.D.
FDA Prescribing Information
Miconazole (Monistat, M-Zole, Micatin) is an anti-fungal drug prescribed to treat vaginal infections and other infections (athlete's foot, ringworm), and severe fungal infections. Side effects, drug interactions, dosage, and pregnancy safety information should be reviewed prior to using this medication.
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clotrimazoleClotrimazole, (Lotrimin AF, Gyne-Lotrimin, Alevazol, Desenex, Pro-Ex Antifungal) is a drug prescribed to treat local fungal infections such as vaginal yeast infections, oral thrush, athlete's foot, and jock itch. Side effects, drug interactions, dosage, and pregnancy safety should be reviewed prior to taking this medication.
Diaper RashA diaper rash is a skin irritation that develops in the diaper-covered region. Most diaper rashes are caused by bacterial or yeast infections, though some may be caused by contact dermatitis or allergic reactions to the diapers and wipes. Cleansing with water and soft cloths, followed by application of petroleum jelly or zinc oxide and frequent diaper changes is the best treatment for a diaper rash.
Drug InteractionsDrug interactions occur frequently. Get facts about the types of drug interactions, what substances or other things that may interact with drugs such as OTC drug and prescription drugs, vitamins, food(s) (grapefruit), and laboratory tests. Find out how to protect yourself from potential drug interactions.
Drugs: What You Should Know About Your DrugsImportant information about your drugs should be reviewed prior to taking any prescription drug. Side effects, drug interactions, warnings and precauctions, dosage, what the drug is used for, what to do if you miss a dose, how the drug is to be stored, and generic vs. brand names.
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