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GENERIC NAME: METRONIDAZOLE SUPPOSITORY - VAGINAL (meh-troh-NID-uh-zole)

USES: Metronidazole is an antibiotic used to treat certain vaginal infections (trichomonas).

HOW TO USE: Using the applicator, insert this medication high into the vagina usually once daily at bedtime; or as directed by your doctor. It is important to continue to use this medication even if you are experiencing your menstrual period. The length of treatment depends on your medical condition and response to therapy. This medication is for vaginal use only. To make the insertion of the suppository easier, you may dip the suppository into water for a few seconds immediately before using it. Consult your pharmacist for more details.

SIDE EFFECTS: Diarrhea, nausea, vomiting, dry mouth, headache, dizziness, drowsiness, or vaginal dryness/burning may occur. If any of these effects persist or worsen, notify your doctor. Tell your doctor immediately if any of these unlikely but serious side effects occur: stomach pain, tingling or numbness of the hands/feet, seizures. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: chest pain, mental/mood changes. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. This medication may cause your urine to darken in color. This harmless effect is temporary and will disappear when the medication is stopped. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: This medication is not recommended for use if you have the following medical conditions: nervous system (neurological) disorders (e.g., seizures, neuropathy), blood problems (e.g., low red and/or white blood cell counts), low blood thyroid levels (hypothyroidism), adrenal gland problem (hypoadrenalism). Tell your doctor your medical history, especially of: liver problems, any allergies. This drug may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. Avoid alcoholic beverages. Also, alcohol use combined with this medication may increase your risk of certain side effects (e.g., vomiting, stomach upset, vision problems). This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medication you may use, especially: disulfiram, lithium, "blood thinners" (e.g., warfarin), certain anti-seizure medicine (e.g., phenobarbital, phenytoin), fluorouracil. This drug may interfere with certain laboratory tests (e.g., liver function tests). Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include: disorientation, seizures.

NOTES: Do not share this medication with others. Laboratory and/or medical tests may be performed to monitor your progress.

MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Store at room temperature between 59 and 86 degrees F (15 and 30 degrees C) away from light and moisture.

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